Procalcitonin: where are we now?

B Hamade, DT Huang - Critical Care Clinics, 2020 - criticalcare.theclinics.com
Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …

[HTML][HTML] Role of procalcitonin use in the management of sepsis

C Gregoriano, E Heilmann, A Molitor… - Journal of thoracic …, 2020 - ncbi.nlm.nih.gov
Important aspects of sepsis management include early diagnosis as well as timely and
specific treatment in the first few hours of triage. However, diagnosis and differentiation from …

Early predictors of in-hospital mortality in patients with COVID-19 in a large American cohort

A Bahl, MN Van Baalen, L Ortiz, NW Chen… - Internal and emergency …, 2020 - Springer
Abstract Coronavirus disease (COVID-19) has aggressively spread across the United States
with numerous fatalities. Risk factors for mortality are poorly described. This was a …

Empfehlungen zur intensivmedizinischen Therapie von Patienten mit COVID‑19

S Kluge, U Janssens, T Welte… - Medizinische Klinik …, 2020 - Springer
Since December 2019, a novel coronavirus (severe acute respiratory syndrome—
coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute …

Clinical characteristics, associated factors, and predicting COVID-19 mortality risk: a retrospective study in Wuhan, China

C Yu, Q Lei, W Li, X Wang, W Liu, X Fan, W Li - American journal of …, 2020 - Elsevier
Introduction COVID-19 has become a serious global pandemic. This study investigates the
clinical characteristics and the risk factors for COVID-19 mortality and establishes a novel …

Utility of procalcitonin as a biomarker for sepsis in children

KJ Downes, JC Fitzgerald, SL Weiss - Journal of clinical …, 2020 - Am Soc Microbiol
Sepsis is a complex process defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. It is associated with significant morbidity and …

[HTML][HTML] Procalcitonin: A promising tool or just another overhyped test?

R Paudel, P Dogra, AA Montgomery-Yates… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Sepsis is the leading cause of death worldwide. Timely administration of antibiotics is
recognized as the cornerstone in the management of sepsis. However, inappropriate use of …

[HTML][HTML] Prognostic values of SOFA score, qSOFA score, and LODS score for patients with sepsis

Y Li, C Yan, Z Gan, X Xi, Z Tan, J Li… - Annals of palliative …, 2020 - apm.amegroups.org
Background: Sepsis continues to carry a high rate of mortality, which makes effective and
simple evaluation methods for predicting the prognosis of septic patients especially …

The ability of Procalcitonin, lactate, white blood cell count and neutrophil-lymphocyte count ratio to predict blood stream infection. Analysis of a large database

PE Marik, E Stephenson - Journal of Critical Care, 2020 - Elsevier
Background The global burden of death due to sepsis is considerable. Early diagnosis is
essential to improve the outcome of this deadly syndrome. Yet, the diagnosis of sepsis is …

Magnetic bead-based electrochemical immunoassays on-drop and on-chip for procalcitonin determination: disposable tools for clinical sepsis diagnosis

Á Molinero-Fernández, M Moreno-Guzmán, MÁ López… - Biosensors, 2020 - mdpi.com
Procalcitonin (PCT) is a known protein biomarker clinically used for the early stages of
sepsis diagnosis and therapy guidance. For its reliable determination, sandwich format …