Targeted exome sequencing identifies five novel loci at genome-wide significance for modulating antidepressant response in patients with major depressive disorder
Z Xu, C Xie, L Xia, Y Yuan, H Zhu, X Huang, C Li… - Translational …, 2020 - nature.com
In order to determine the role of single nucleotide variants (SNVs) in modulating
antidepressant response, we conducted a study, consisting of 929 major depressive …
antidepressant response, we conducted a study, consisting of 929 major depressive …
A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: Confirmation with meta-analysis of other antipsychotic drugs
A Yoshikawa, J Li, HY Meltzer - The pharmacogenomics journal, 2020 - nature.com
Stimulation of the serotonin (5-HT) 1A receptor (HTR1A) has been shown to contribute to the
mechanism of action of some atypical antipsychotic drugs (APDs), including clozapine and …
mechanism of action of some atypical antipsychotic drugs (APDs), including clozapine and …
Gene expression and response prediction to amisulpride in the OPTiMiSE first episode psychoses
R Troudet, WBH Ali, D Bacq-Daian… - …, 2020 - nature.com
A fundamental shortcoming in the current treatment of schizophrenia is the lack of valid
criteria to predict who will respond to antipsychotic treatment. The identification of blood …
criteria to predict who will respond to antipsychotic treatment. The identification of blood …
An integrative analysis of genetics, brain structure, and childhood trauma in antipsychotic treatment response: toward a unified view of treatment outcome in …
E Frickel - 2020 - scholar.sun.ac.za
Schizophrenia is a debilitating neuropsychiatric disorder affecting approximately 1% of the
global population. Unfortunately, antipsychotic treatment is ineffective in 50% of patients …
global population. Unfortunately, antipsychotic treatment is ineffective in 50% of patients …