MicroRNAs in gray and white matter multiple sclerosis lesions: impact on pathophysiology

S Teuber‐Hanselmann, E Meinl… - The Journal of …, 2020 - Wiley Online Library
Multiple sclerosis (MS) is a chronic disease of the CNS, hallmarked by inflammation and
demyelination. Early stages of the disease frequently show active lesions containing …

Epigenetics in multiple sclerosis

VSF Chan - Epigenetics in allergy and autoimmunity, 2020 - Springer
Multiple sclerosis (MS) is an aggravating autoimmune disease that cripples young patients
slowly with physical, sensory and cognitive deficits. The break of self-tolerance to neuronal …

Differentiation of pathogenic Th17 cells is negatively regulated by Let-7 microRNAs in a mouse model of multiple sclerosis

CC Angelou, AC Wells, J Vijayaraghavan… - Frontiers in …, 2020 - frontiersin.org
Multiple sclerosis (MS) is a disabling demyelinating autoimmune disorder of the central
nervous system (CNS) which is driven by IL-23-and IL-1β-induced autoreactive Th17 cells …

CSF microRNAs discriminate MS activity and share similarity to other neuroinflammatory disorders

O Perdaens, HA Dang, L D'Auria… - Neurology …, 2020 - AAN Enterprises
Objective To perform a comprehensive multicompartment analysis of microRNA (miRNA)
expression in multiple sclerosis (MS) linked to disease activity and compared with other …

Downregulation of cancer-associated lncRNAs in peripheral blood of multiple sclerosis patients

A Safa, M Taheri, H Fallah, T Salmani… - Journal of Molecular …, 2020 - Springer
Recent studies have shown contribution of long non-coding RNAs (lncRNAs) in the
pathogenesis of immune-related disorders including multiple sclerosis (MS). Based on the …

The rs4759314 SNP within Hotair lncRNA is associated with risk of multiple sclerosis

M Taheri, R Noroozi, S Sadeghpour, MD Omrani… - Multiple Sclerosis and …, 2020 - Elsevier
Recent studies have demonstrated the role of long non-coding RNAs (lncRNAs) in the
pathophysiology of autoimmune disorders such as multiple sclerosis (MS). Among these …

The relationship of the mechanisms of the pathogenesis of multiple sclerosis and the expression of endogenous retroviruses

VR Lezhnyova, EV Martynova, TI Khaiboullin… - Biology, 2020 - mdpi.com
Simple Summary Multiple sclerosis is a neurodegenerative disease of the central nervous
system, develops at an early age and often leads to a disability. The etiological cause of the …

[PDF][PDF] Distinctive deregulation of miR-27a and miR-27b in relapsing remitting multiple sclerosis

J Shafiei, F Heidari, E Khashen… - Journal of Basic …, 2020 - jbrms.medilam.ac.ir
Introduction: Previous studies have proposed that microRNAs (miRNAs) expression might
be responsible for immunological features associated with multiple sclerosis (MS) …

[PDF][PDF] Biological reflections in body fluids of multiple sclerosis progression and multiple sclerosis-related fatigue

A Malekzadeh - 2020 - research.vu.nl
There is a strong unmet clinical need for objective body fluid biomarkers to assist early
diagnosis and estimate long-term prognosis, monitor treatment response and predict …

Regulation of Neuroinflammatory Factors by Neuroprotective MicroRNAs in HIV-1 Infected Microglia

S Amirova - 2020 - d-scholarship.pitt.edu
Despite successful antiretroviral therapy (ART), more than half of individuals living with HIV-
1 exhibit HIV-1 Associated Neurocognitive Disorder (HAND). Individuals with HAND …