Pathophysiology and treatment of stroke: present status and future perspectives

D Kuriakose, Z Xiao - International journal of molecular sciences, 2020 - mdpi.com
Stroke is the second leading cause of death and a major contributor to disability worldwide.
The prevalence of stroke is highest in developing countries, with ischemic stroke being the …

Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress

X Wu, J Jiang, Z Gu, J Zhang, Y Chen, X Liu - Stem cell research & …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Clinical application of virtual reality for upper limb motor rehabilitation in stroke: review of technologies and clinical evidence

WS Kim, S Cho, J Ku, Y Kim, K Lee, HJ Hwang… - Journal of clinical …, 2020 - mdpi.com
Neurorehabilitation for stroke is important for upper limb motor recovery. Conventional
rehabilitation such as occupational therapy has been used, but novel technologies are …

Epilepsy in older people

A Sen, N Jette, M Husain, JW Sander - The Lancet, 2020 - thelancet.com
Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

Discovering Anti-Cancer Drugs via Computational Methods

W Cui, A Aouidate, S Wang, Q Yu, Y Li… - Frontiers in …, 2020 - frontiersin.org
New drug discovery has been acknowledged as a complicated, expensive, time-consuming,
and challenging project. It has been estimated that around 12 years and 2.7 billion USD, on …

Integrated and patient-centred management of Parkinson's disease: a network model for reshaping chronic neurological care

BR Bloem, EJ Henderson, ER Dorsey… - The Lancet …, 2020 - thelancet.com
Chronic neurological diseases are the leading cause of disability globally. Yet, our health-
care systems are not designed to meet the needs of many patients with chronic neurological …

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke

Y Xia, X Ling, G Hu, Q Zhu, J Zhang, Q Li… - Stem cell research & …, 2020 - Springer
Background Small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSC)
derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to …

Platelets as mediators of neuroinflammation and thrombosis

E Rawish, H Nording, T Münte, HF Langer - Frontiers in immunology, 2020 - frontiersin.org
Beyond platelets function in hemostasis, there is emerging evidence to suggest that platelets
contribute crucially to inflammation and immune responses. Therefore, considering the …

You've got male: Sex and the microbiota-gut-brain axis across the lifespan

M Jaggar, K Rea, S Spichak, TG Dinan… - Frontiers in …, 2020 - Elsevier
Sex is a critical factor in the diagnosis and development of a number of mental health
disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease …

HIV and cardiovascular disease

K So-Armah, LA Benjamin, GS Bloomfield… - The lancet HIV, 2020 - thelancet.com
HIV-related cardiovascular disease research is predominantly from Europe and North
America. Of the estimated 37· 9 million people living with HIV worldwide, 25· 6 million live in …