[图书][B] Physical mechanisms of bacterial killing by histones

T Doolin, S Gross, A Siryaporn - 2020 - Springer
Antibiotic resistance is a global epidemic, becoming increasingly pressing due to its rapid
spread. There is thus a critical need to develop new therapeutic approaches. In addition to …

A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy

G Manzo, CK Hind, PM Ferguson, RT Amison… - Communications …, 2020 - nature.com
Antimicrobial peptides (AMPs) are a potential alternative to classical antibiotics that are yet
to achieve a therapeutic breakthrough for treatment of systemic infections. The antibacterial …

Synthesis of Fmoc-triazine amino acids and its application in the synthesis of short antibacterial peptidomimetics

P Gunasekaran, EY Kim, J Lee, EK Ryu… - International Journal of …, 2020 - mdpi.com
To combat the escalating rise of antibacterial resistance, the development of antimicrobial
peptides (AMPs) with a unique mode of action is considered an attractive strategy. However …

The Study of HIV-1 Vpr-Membrane and Vpr-hVDAC-1 Interactions by Graphene Field-Effect Transistor Biosensors

P Zhong, CH Liu, YT Chen, TY Yu - ACS Applied Bio Materials, 2020 - ACS Publications
The viral protein R (Vpr) of human immunodeficiency virus 1 (HIV-1) is involved in many
cellular processes during the viral life cycle; however, its associated mechanisms remain …

Physicochemical Features and Peculiarities of Interaction of Antimicrobial Peptides with the Membrane

M Pirtskhalava, B Vishnepolsky, M Grigolava - arXiv preprint arXiv …, 2020 - arxiv.org
Antimicrobial peptides (AMPs) are anti-infectives that have potential as a novel and
untapped class of biotherapeutics. Modes of action of antimicrobial peptides imply …