[HTML][HTML] Host genetics at the intersection of autoimmunity and COVID-19: a potential key for heterogeneous COVID-19 severity

T Karaderi, H Bareke, I Kunter, A Seytanoglu… - Frontiers in …, 2020 - frontiersin.org
COVID-19 presentation is very heterogeneous across cases, and host factors are at the
forefront for the variables affecting the disease manifestation. The immune system has …

Germline immunoglobulin genes: disease susceptibility genes hidden in plain sight?

AM Collins, G Yaari, AJ Shepherd, W Lees… - Current Opinion in …, 2020 - Elsevier
Immunoglobulin genes are rarely considered as disease susceptibility genes despite their
obvious and central contributions to immune function. This appears to be a consequence of …

[HTML][HTML] COVID-19 and the liver: What do we know after six months of the pandemic?

NA Fierro - Annals of Hepatology, 2020 - Elsevier
Despite liver injury in patients infected with severe acute respiratory syndrome (SARS)
coronavirus (CoV)-2 (SARS-CoV-2) is associated with prolonged hospitalization, and liver …

[HTML][HTML] Retrospective in silico HLA predictions from COVID-19 patients reveal alleles associated with disease prognosis

RL Warren, I Birol - MedRxiv, 2020 - ncbi.nlm.nih.gov
Background: The Human Leukocyte Antigen (HLA) gene locus plays a fundamental role in
human immunity, and it is established that certain HLA alleles are disease determinants …

Пандемия COVID-19 как индикатор «белых пятен» в эпидемиологии и инфекционной патологии

МВ Супотницкий - Вестник войск РХБ защиты, 2020 - journal.soyuz-veteranov-rhbz.ru
Аннотация Пандемия COVID-19 (Coronavirus Disease 2019) выявила множество
«белых пятен» в эпидемиологической науке как раз тогда, когда у человечества …

[HTML][HTML] A “window of therapeutic opportunity” for anti-cytokine therapy in patients with coronavirus disease 2019

L De Stefano, F Bobbio-Pallavicini, A Manzo… - Frontiers in …, 2020 - frontiersin.org
The effects of cytokine inhibition in the different phases of the severe coronavirus disease
2019 (COVID-19) are currently at the center of intense debate, and preliminary results from …

The intersection between COVID-19, the gene family of ACE2 and Alzheimer's disease

MM Haghighi, EG Kakhki, C Sato… - Neuroscience …, 2020 - journals.sagepub.com
We reviewed factors that might influence COVID-19 outcomes (eg, neurological symptoms),
including the link to Alzheimer's disease. Since the virus triggers COVID-19 infection through …

[HTML][HTML] Impact of COVID-19 pandemic on pediatrics and pediatric transplantation programs

S Lobritto, L Danziger-Isakov, MG Michaels… - Frontiers in …, 2020 - frontiersin.org
COVID-19 has dramatically altered the health care landscape and disrupted global health
and world economics in ways that are still being measured. Its impact on children with …

[HTML][HTML] Interplay between air travel, genome integrity, and COVID-19 risk vis-a-vis flight crew

SM Toprani, C Scheibler, ZD Nagel - Frontiers in Public Health, 2020 - frontiersin.org
During air travel, flight crew (flight attendants, pilots) can be exposed to numerous flight-
related environmental DNA damaging agents that may be at the root of an excess risk of …

No impact of cancer and plague-relevant FPR1 polymorphisms on COVID-19

A Petrazzuolo, J Le Naour, E Vacchelli… - …, 2020 - Taylor & Francis
ABSTRACT Formyl peptide receptor 1 (FPR1) is a pattern-recognition receptor that detects
bacterial as well as endogenous danger-associated molecular patterns to trigger innate …