Cubilin, the intrinsic factor-vitamin B12 receptor in development and disease

R Kozyraki, O Cases - Current medicinal chemistry, 2020 - ingentaconnect.com
Gp280/Intrinsic factor-vitamin B12 receptor/Cubilin (CUBN) is a large endocytic receptor
serving multiple functions in vitamin B12 homeostasis, renal reabsorption of protein or toxic …

Hepatic nuclear factor 1 alpha (HNF-1α) in human physiology and molecular medicine

S Begum - Current Molecular Pharmacology, 2020 - ingentaconnect.com
The transcription factors (TFs) play a crucial role in the modulation of specific gene
transcription networks. One of the hepatocyte nuclear factors (HNFs) family's member …

[HTML][HTML] Transgenic zebrafish modeling low-molecular-weight proteinuria and lysosomal storage diseases

Z Chen, A Luciani, JM Mateos, G Barmettler, RH Giles… - Kidney international, 2020 - Elsevier
Epithelial cells lining the proximal tubule of the kidney reabsorb and metabolize most of the
filtered low-molecular-weight proteins through receptor-mediated endocytosis and …

The Role of Hepatocyte Nuclear Factor 4a in Renal Proximal Tubule Development

SS Marable - 2020 - search.proquest.com
Nephron segmentation is a poorly understood process that forms four distinct regions of the
nephron: the renal corpuscle, the proximal tubule, the loop of Henle, and the distal tubule …