Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …

Tumors are complex multicellular heterogeneous systems comprised of components that
interact with and modify one another. Tumor development depends on multiple factors …

Tumor associated angiogenesis is the development of new blood vessels in response to
proteins secreted by tumor cells. These new blood vessels allow tumors to continue to grow …

The 2019 novel coronavirus, SARS-CoV-2, is an emerging pathogen of critical significance
to international public health. Knowledge of the interplay between molecular-scale virus …

A huge variety of mathematical models have been used to investigate collective cell
migration. The aim of this brief review is twofold: to present a number of modelling …

The term cancer covers a multitude of bodily diseases, broadly categorised by having cells
which do not behave normally. Since cancer cells can arise from any type of cell in the body …

We provide an overview on the use of biological assays to calibrate and initialize
mechanism-based models of cancer phenomena. Although artificial intelligence methods …

Fibroblasts as key components of tumor microenvironment show different features in the
interaction with cancer cells. Although, Normal fibroblasts demonstrate anti-tumor effects …

Background: Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in
adults and Temozolomide (TMZ) is an effective chemotherapeutic agent for its treatment. In …

Centre-based or cell-centre models are a framework for the computational study of
multicellular systems with widespread use in cancer modelling and computational …