Cannabis use and the risk for psychosis and affective disorders

L Sideli, H Quigley, C La Cascia… - Journal of dual …, 2020 - Taylor & Francis
Objective: This review discusses the relationship between cannabis use and psychotic,
bipolar, depressive, and anxiety disorders, as well as suicide. It summarizes epidemiological …

[HTML][HTML] Cannabis use during pregnancy and its relationship with fetal developmental outcomes and psychiatric disorders. A systematic review

C Roncero, I Valriberas-Herrero… - Reproductive …, 2020 - Springer
Introduction This study analyze factors associated to cannabis use in pregnant women, its
perceived availability, its risk perception and the relationship between prenatal exposure to …

[HTML][HTML] Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and …

R Tao, C Li, AE Jaffe, JH Shin, A Deep-Soboslay… - Translational …, 2020 - nature.com
Beyond being one the most widely used psychoactive drugs in the world, cannabis has
been identified as an environmental risk factor for psychosis. Though the relationship …

[HTML][HTML] How can drug metabolism and transporter genetics inform psychotropic prescribing?

B Carvalho Henriques, EH Yang, D Lapetina… - Frontiers in …, 2020 - frontiersin.org
Many genetic variants in drug metabolizing enzymes and transporters have been shown to
be relevant for treating psychiatric disorders. Associations are strong enough to feature on …

[HTML][HTML] Factors moderating the association between cannabis use and psychosis risk: a systematic review

SJ Van der Steur, A Batalla, MG Bossong - Brain sciences, 2020 - mdpi.com
Increasing evidence indicates a relationship between cannabis use and psychosis risk.
Specific factors, such as determinants of cannabis use or the genetic profile of cannabis …

Urbanicity: The need for new avenues to explore the link between urban living and psychosis

L Abrahamyan Empson, PS Baumann… - Early intervention in …, 2020 - Wiley Online Library
Aim A growing body of evidence suggests that urban living contributes to the development of
psychosis. However, the mechanisms underlying this phenomenon remain unclear. This …

[HTML][HTML] Effects of cannabidiol and delta-9-tetrahydrocannabinol on emotion, cognition, and attention: a double-blind, placebo-controlled, randomized experimental …

T Woelfl, C Rohleder, JK Mueller, B Lange… - Frontiers in …, 2020 - frontiersin.org
The two main phytocannabinoids—delta-9-tetrahydrocannabinol (THC) and cannabidiol
(CBD)—have been extensively studied, and it has been shown that THC can induce …

Effects of cannabis exposure in the prenatal and adolescent periods: Preclinical and clinical studies in both sexes

J Tirado-Muñoz, AB Lopez-Rodriguez… - Frontiers in …, 2020 - Elsevier
Cannabis is the most commonly used illicit drug among adolescents and young adults,
including pregnant women. There is substantial evidence for a significant association …

Childhood trauma and substance use underlying psychosis: a systematic review

E Setién-Suero, P Suárez-Pinilla, A Ferro… - European journal of …, 2020 - Taylor & Francis
Background: Schizophrenia spectrum disorders (SSD) are mental diseases caused by a
combination of genetic susceptibility and a number of environmental factors. Among these …

[HTML][HTML] Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort

AJ Osborne, JF Pearson, AJ Noble, NJ Gemmell… - Translational …, 2020 - nature.com
Cannabis use is of increasing public health interest globally. Here we examined the effect of
heavy cannabis use, with and without tobacco, on genome-wide DNA methylation in a …