Clinical value of DNA methylation markers in autoimmune rheumatic diseases
E Ballestar, AH Sawalha, Q Lu - Nature Reviews Rheumatology, 2020 - nature.com
Methylation of cytosine residues in DNA, the best studied epigenetic modification, is
associated with gene transcription and nuclear organization, and ultimately the function of a …
associated with gene transcription and nuclear organization, and ultimately the function of a …
DNA methylation in human sperm: a systematic review
BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …
A methylation study of long-term depression risk
Recurrent and chronic major depressive disorder (MDD) accounts for a substantial part of
the disease burden because this course is most prevalent and typically requires long-term …
the disease burden because this course is most prevalent and typically requires long-term …
Age-associated epigenetic change in chimpanzees and humans
EE Guevara, RR Lawler, N Staes… - … of the Royal …, 2020 - royalsocietypublishing.org
Methylation levels have been shown to change with age at sites across the human genome.
Change at some of these sites is so consistent across individuals that it can be used as an …
Change at some of these sites is so consistent across individuals that it can be used as an …
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations
F Åsenius, TJ Gorrie-Stone, A Brew… - PLoS …, 2020 - journals.plos.org
Epidemiological research suggests that paternal obesity may increase the risk of fathering
small for gestational age offspring. Studies in non-human mammals indicate that such …
small for gestational age offspring. Studies in non-human mammals indicate that such …
Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits
ABSTRACT DNA methylation (DNAm) and microRNAs (miRNAs) have been implicated in a
wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not …
wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not …
Membership inference against DNA methylation databases
Biomedical data sharing is one of the key elements fostering the advancement of biomedical
research but poses severe risks towards the privacy of individuals contributing their data, as …
research but poses severe risks towards the privacy of individuals contributing their data, as …
A genome-wide multiphenotypic association analysis identified common candidate genes for subjective well-being, depressive symptoms and neuroticism
X Chu, L Liu, Y Wen, P Li, B Cheng, S Cheng… - Journal of Psychiatric …, 2020 - Elsevier
Abstract Subjective well-being (SWB), depressive symptoms, and neuroticism are common
and vital traits of mental disorders. Genetic mechanisms of SWB, depressive symptoms and …
and vital traits of mental disorders. Genetic mechanisms of SWB, depressive symptoms and …
Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia
X Qi, F Guan, Y Wen, P Li, M Ma, S Cheng… - Progress in Neuro …, 2020 - Elsevier
Background Schizophrenia (SCZ) is a severe mental disorder. Both environmental and
genetic factors contribute to the development of SCZ. The estimated heritability of SCZ is …
genetic factors contribute to the development of SCZ. The estimated heritability of SCZ is …
Mendelian randomization identifies CpG methylation sites with mediation effects for genetic influences on BMD in peripheral blood monocytes
Osteoporosis is mainly characterized by low bone mineral density (BMD) and is an
increasingly serious public health concern. DNA methylation is a major epigenetic …
increasingly serious public health concern. DNA methylation is a major epigenetic …