Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia

MT Gebru, HG Wang - Journal of Hematology & Oncology, 2020 - Springer
Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene
mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid …

FLT3LG-a biomarker reflecting clinical responses to the immunogenic cell death inducer oxaliplatin

JG Pol, J Le Naour, G Kroemer - Oncoimmunology, 2020 - Taylor & Francis
The fms-related tyrosine kinase 3 (FLT3) ligand (FLT3LG) binds to FLT3 on dendritic cells to
stimulate their differentiation and expansion, hence facilitating tumor antigen cross …

Mechanism of Drug Tolerance in FLT3 Mutant Acute Myeloid Leukemia

M Gebru - 2020 - etda.libraries.psu.edu
AML is a heterogeneous disease caused by several mutations and cytogenetic
abnormalities affecting differentiation and proliferation of myeloid lineage cells. FLT3 is a …