Obesity subtypes, related biomarkers & heterogeneity

LPC Mayoral, GM Andrade, EPC Mayoral… - Indian Journal of …, 2020 - journals.lww.com
Obesity is a serious medical condition worldwide, which needs new approaches and
recognized international consensus in treating diseases leading to morbidity. The aim of this …

Metabolic regulation of kisspeptin—the link between energy balance and reproduction

VM Navarro - Nature reviews endocrinology, 2020 - nature.com
Hypothalamic kisspeptin neurons serve as the nodal regulatory centre of reproductive
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures–2019 update: cosponsored …

JI Mechanick, C Apovian, S Brethauer… - Surgery for Obesity and …, 2020 - Elsevier
Objective The development of these updated clinical practice guidelines (CPG) was
commissioned by the American Association of Clinical Endocrinologists, The Obesity …

Genetic determinants of childhood obesity

SH Littleton, RI Berkowitz, SFA Grant - Molecular diagnosis & therapy, 2020 - Springer
Obesity represents a major health burden to both developed and developing countries.
Furthermore, the incidence of obesity is increasing in children. Obesity contributes …

Adipose tissue development and expansion from the womb to adolescence: an overview

CE Orsso, E Colin-Ramirez, CJ Field, KL Madsen… - Nutrients, 2020 - mdpi.com
Prevalence rates of pediatric obesity continue to rise worldwide. Adipose tissue (AT)
development and expansion initiate in the fetus and extend throughout the lifespan. This …

Chronic stress, epigenetics, and adipose tissue metabolism in the obese state

Y Xiao, D Liu, MA Cline, ER Gilbert - Nutrition & metabolism, 2020 - Springer
In obesity, endocrine and metabolic perturbations, including those induced by chronic
activation of the hypothalamus–pituitary–adrenal axis, are associated with the accumulation …

Alteration of gut microbiota affects expression of adiponectin and resistin through modifying DNA methylation in high-fat diet-induced obese mice

H Yao, C Fan, Y Lu, X Fan, L Xia, P Li, R Wang, T Tang… - Genes & nutrition, 2020 - Springer
Background Adiponectin and resistin are typically secreted by the adipose tissue and are
abnormally expressed in obesity. However, the underlying influential factors and …

Converging relationships of obesity and hyperuricemia with special reference to metabolic disorders and plausible therapeutic implications

M Gong, S Wen, T Nguyen, C Wang, J Jin… - … Syndrome and Obesity, 2020 - Taylor & Francis
Background Obesity and hyperuricemia mutually influence metabolic syndrome. This study
discusses the metabolic relationships between obesity and hyperuricemia in terms of …

The effect of excess body fat on female and male reproduction

G Mintziori, MP Nigdelis, H Mathew, A Mousiolis… - Metabolism, 2020 - Elsevier
The dramatic increase in the prevalence of obesity coincides with a decline in reproductive
health indices in both sexes. Energy excess mediates changes to the regulatory …

Omics biomarkers in obesity: novel etiological insights and targets for precision prevention

K Aleksandrova, C Egea Rodrigues, A Floegel… - Current obesity …, 2020 - Springer
Abstract Purpose of Review Omics-based technologies were suggested to provide an
advanced understanding of obesity etiology and its metabolic consequences. This review …