Mass spectrometry (MS)-based omics technologies are now widely used to profile small
molecules in multiple matrices to confer comprehensive snapshots of cellular metabolic …

Prospective observational studies support the use of long-chain omega-3 polyunsaturated
fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; …

Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …

The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the
accompanying rise of its complications, including cardiovascular disease, necessitates our …

Background We aimed to explore metabolite biomarkers that could be used to identify pre-
diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis …

Glycine levels are inversely associated with branched-chain amino acids (BCAAs) and
cardiometabolic disease phenotypes, but biochemical mechanisms that explain these …

Background Women with a history of gestational diabetes mellitus (GDM) have a 7-fold
higher risk of developing type 2 diabetes (T2D) during midlife and an elevated risk of …

ABSTRACT Type 2 diabetes (T2D) is a complex metabolic syndrome characterized by
insulin dysfunction and abnormalities in glucose and lipid metabolism. The gut microbiome …

Diabetes mellitus is the most prevalent endocrine disease in the world and is likely to be the
major epidemic in human history. In current years, many modern anti-diabetic medicines …

Background Glycolysis/gluconeogenesis and tricarboxylic acid (TCA) cycle metabolites
have been associated with type 2 diabetes (T2D). However, the associations of these …