Biomarkers for prostate cancer: prostate-specific antigen and beyond

MJ Duffy - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In recent years, several new biomarkers supplementing the role of prostate-specific antigen
(PSA) have become available for men with prostate cancer. Although widely used in an ad …

Lung cancer screening with low-dose CT: a meta-analysis

RM Hoffman, RP Atallah, RD Struble… - Journal of general internal …, 2020 - Springer
Background Randomized controlled trials have evaluated the efficacy of low-dose CT
(LDCT) lung cancer screening on lung cancer (LC) outcomes. Objective Meta-analyze LDCT …

Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

C Parker, E Castro, K Fizazi, A Heidenreich… - Annals of …, 2020 - annalsofoncology.org
Subclinical prostate cancer is common in men> 50 years. Population-based screening of
men aged between 55 and 69 years, using prostate-specific antigen (PSA) testing, has been …

Reconsidering prostate cancer mortality—the future of PSA screening

HG Welch, PC Albertsen - New England Journal of Medicine, 2020 - Mass Medical Soc
Reconsidering Prostate Cancer Mortality Since PSA screening and the treatment that may
follow result in trading off one cause of death for another, rather than extending life …

Prostate cancer incidence across stage, NCCN risk groups, and age before and after USPSTF Grade D recommendations against prostate‐specific antigen screening …

SS Butler, V Muralidhar, SG Zhao, NN Sanford… - Cancer, 2020 - Wiley Online Library
Background We sought to determine the extent to which US Preventive Services Task Force
(USPSTF) 2012 Grade D recommendations against prostate‐specific antigen screening may …

Prostate cancer screening and treatment: where have we come from and where are we going?

PC Albertsen - BJU international, 2020 - Wiley Online Library
Objective To evaluate the current prostate cancer screening and treatment paradigm in light
of recently published long‐term results of major screening and treatment trials. Methods …

[HTML][HTML] Reconsidering the trade-offs of prostate cancer screening

JE Shoag, YA Nyame, R Gulati, R Etzioni… - The New England …, 2020 - ncbi.nlm.nih.gov
After the widespread adoption of prostate-specific antigen (PSA) screening in the early
1990s, prostate cancer diagnoses increased rapidly while death rates halved over the …

Multiparametric MRI‐Based Radiomics for Prostate Cancer Screening With PSA in 4–10 ng/mL to Reduce Unnecessary Biopsies

Y Qi, S Zhang, J Wei, G Zhang, J Lei… - Journal of Magnetic …, 2020 - Wiley Online Library
Background Whether men with a prostate‐specific antigen (PSA) level of 4–10 ng/mL should
be recommended for a biopsy is clinically challenging. Purpose To develop and validate a …

Comparison of machine learning algorithms to predict clinically significant prostate cancer of the peripheral zone with multiparametric MRI using clinical assessment …

S Bernatz, J Ackermann, P Mandel, B Kaltenbach… - European …, 2020 - Springer
Objectives To analyze the performance of radiological assessment categories and
quantitative computational analysis of apparent diffusion coefficient (ADC) maps using …

Autonomous detection and classification of PI-RADS lesions in an MRI screening population incorporating multicenter-labeled deep learning and biparametric …

DJ Winkel, C Wetterauer, MO Matthias, B Lou, B Shi… - Diagnostics, 2020 - mdpi.com
Background: Opportunistic prostate cancer (PCa) screening is a controversial topic.
Magnetic resonance imaging (MRI) has proven to detect prostate cancer with a high …