Oxazole compounds, including one nitrogen atom and one oxygen atom in a five-membered
heterocyclic ring, are present in various biological activities. Due to binding with a …

A new member of the class metallo-β-lactamase (MBL), New Delhi metallo-beta-lactamase 1
(NDM-1) has emerged recently as a leading threat to the treatment of infections that have …

New Delhi metallo-β-lactamase-1 (NDM-1) has recently emerged as a global threat because
of its ability to confer resistance to all common β-lactam antibiotics. Understanding the …

The fungal natural product aspergillomarasmine A (AMA) has been identified as a
noncompetitive inhibitor of New Delhi metallo‐β‐lactamase‐1 (NDM‐1) that inhibits by …

Carbapenem-resistant Enterobacteriaceae (CRE) producing New Delhi metallo-β-
lactamase (NDM-1) cause untreatable bacterial infections, posing a significant threat to …

NDM-1 can hydrolyze nearly all available β-lactam antibiotics, including carbapenems. NDM-
1 producing bacterial strains are worldwide threats. It is still very challenging to find a potent …

The most common mechanism of the resistance to β-lactam antibiotics is the
expIdentification of cisplatin and palladiuression of β-lactamases, which can hydrolyze the β …

Carbapenem-resistant Enterobacteriaceae continue to threaten human health worldwide
with few effective treatment options. New Delhi metallo-β-lactamase (NDM) enzymes are a …

New Delhi metallo-β-lactamase (NDM-1) is the most recent addition to the class of metallo-β-
lactamases (MBLs). This enzyme leads to antibiotic resistance in clinical treatments owing to …

细菌中抗生素耐药性的迅速发展威胁着将人类带回到“后抗生素时代”. 新德里金属β-
内酰胺酶(NDM-1) 几乎可以水解所有的β-内酰胺抗生素, 包括碳青霉烯. 携带blaNDM-1 …