Creatinine: from physiology to clinical application

K Kashani, MH Rosner, M Ostermann - European journal of internal …, 2020 - Elsevier
Estimating static kidney function accurately and detecting changes in kidney function in a
timely fashion are challenging but critically important tasks. Serum creatinine is the most …

Renal functional reserve: from physiological phenomenon to clinical biomarker and beyond

AH Jufar, YR Lankadeva, CN May… - American Journal …, 2020 - journals.physiology.org
Glomerular filtration rate (GFR) is acutely increased following a high-protein meal or
systemic infusion of amino acids. The mechanisms underlying this renal functional response …

Diagnostic utility of protein to creatinine ratio (P/C ratio) in spot urine sample within routine clinical practice

J Kamińska, V Dymicka-Piekarska… - Critical reviews in …, 2020 - Taylor & Francis
The spot (random) urine protein to creatinine ratio (P/C ratio) is an alternative, fast and
simple method of detecting and estimating the quantitative assessment of proteinuria. The …

[HTML][HTML] Associations between blood volatile organic compounds, and changes in hematologic and biochemical profiles, in a population-based study

S Cakmak, C Cole, C Hebbern, J Andrade… - Environment …, 2020 - Elsevier
Objective To investigate the influence of volatile organic compound (VOC) levels in blood,
on hematological and serum biochemical parameters in the Canadian population. Methods …

Augmented renal clearance in pediatric intensive care: are we undertreating our sickest patients?

E Dhont, T Van Der Heggen, A De Jaeger… - Pediatric …, 2020 - Springer
Many critically ill patients display a supraphysiological renal function with enhanced renal
perfusion and glomerular hyperfiltration. This phenomenon described as augmented renal …

Proenkephalin compared to conventional methods to assess kidney function in critically ill sepsis patients

R Beunders, R van Groenendael, GP Leijte, M Kox… - Shock, 2020 - journals.lww.com
Background: The assessment of renal function in clinical practice remains challenging.
Using creatinine to assess the glomerular filtration rate (GFR) is notoriously inaccurate, and …

The many faces of matrix metalloproteinase-7 in kidney diseases

Z Liu, RJ Tan, Y Liu - Biomolecules, 2020 - mdpi.com
Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-dependent endopeptidase that is
implicated in regulating kidney homeostasis and diseases. MMP-7 is produced as an …

[HTML][HTML] How to determine kidney function in cancer patients?

B Sprangers, A Abudayyeh, S Latcha… - European Journal of …, 2020 - Elsevier
A precise and efficient method for estimating kidney function in cancer patients is important
to determine their eligibility for clinical trials and surgery and to allow for appropriate dose …

Renal hyperfiltration as a risk factor for chronic kidney disease: a health checkup cohort study

SW Oh, JH Yang, MG Kim, WY Cho, SK Jo - PLoS One, 2020 - journals.plos.org
Introduction Renal hyperfiltration (RHF) has been found to be an independent predictor of
adverse cardiovascular outcome. However, it remains uncertain whether it is precursor of …

Living kidney donor evaluation

G Claisse, F Gaillard, C Mariat - Transplantation, 2020 - journals.lww.com
Long-term safety of living kidney donation (LKD), especially for young donors, has become a
real matter of concern in the transplant community and may contribute to creating resistance …