[HTML][HTML] Polygenic risk scores shed light on the relationship between schizophrenia and cognitive functioning: review and meta-analysis

J Mallet, Y Le Strat, C Dubertret, P Gorwood - Journal of clinical medicine, 2020 - mdpi.com
Schizophrenia is a multifactorial disease associated with widespread cognitive impairment.
Although cognitive deficits are one of the factors most strongly associated with functional …

[HTML][HTML] Shared polygenic risk for ADHD, executive dysfunction and other psychiatric disorders

S Chang, L Yang, Y Wang, SV Faraone - Translational Psychiatry, 2020 - nature.com
Many psychiatric disorders are associated with impaired executive functioning (EF). The
associated EF component varies by psychiatric disorders, and this variation might be due to …

Why does age of onset predict clinical severity in schizophrenia? A multiplex extended pedigree study

CW Musket, SS Kuo, PE Rupert… - American Journal of …, 2020 - Wiley Online Library
Schizophrenia has substantial variation in symptom severity, course of illness, and overall
functioning. Earlier age of onset (AOO) is consistently associated with negative outcomes …

Cortical gyrification, psychotic-like experiences, and cognitive performance in nonclinical subjects

U Evermann, C Gaser, B Besteher… - Schizophrenia …, 2020 - academic.oup.com
Background Psychotic-like experiences (PLE) are present in nonclinical populations, yet
their association with brain structural variation, especially markers of early …

The association between exposure to herpes simplex virus type 1 (HSV-1) and cognitive functioning in schizophrenia: a meta-analysis

F Dickerson, JR Schroeder, V Nimgaonkar, J Gold… - Psychiatry …, 2020 - Elsevier
Cognitive deficits are characteristic of schizophrenia but their etiology is not understood.
Previous studies show an association between viral exposures and cognitive impairment …

Childhood infection and subsequent risk of psychotic disorders in adults: A systematic review and meta-analysis

H Jiang, X Zhang, L Pan, Y Ma - Asian Journal of Psychiatry, 2020 - Elsevier
Objective The effects of childhood infection exposure on the risk of subsequent psychosis
are unclear and no overview is available. We conducted a meta-analysis to assess the link …

The effect of the AKT1 gene and cannabis use on cognitive performance in healthy subjects

M Fatjó-Vilas, J Soler, MI Ibáñez… - Journal of …, 2020 - journals.sagepub.com
Background: Evidence suggests that the AKT1 gene may modulate the degree to which
cannabis use induces cognitive alterations in patients with a psychotic disorder. Aim: To …

Familial aggregation analysis of cognitive performance in early-onset bipolar disorder

J Soler, S Lera-Miguel, L Lázaro, R Calvo… - European Child & …, 2020 - Springer
We analysed the familial aggregation (familiality) of cognitive dimensions and explored their
role as liability markers for early-onset bipolar disorder (EOBD). The sample comprised 99 …

Heritability of memory functions and related brain volumes: a schizophrenia spectrum study of 214 twins

CK Lemvigh, RM Brouwer, BJ Sahakian… - Schizophrenia …, 2020 - academic.oup.com
Background Memory performance is heritable and shares partial genetic etiology with
schizophrenia. How the genetic overlap between memory and schizophrenia is related to …

Psychotische Störungen und Schizophrenie

A Clamor, I Frantz, TM Lincoln - Klinische Psychologie & Psychotherapie, 2020 - Springer
Psychotische Störungen sind durch die sog. Positiv-und Negativsymptomatik
gekennzeichnet. Positivsymptome sind Wahn (häufig Verfolgungswahn), Halluzinationen …