Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …

Traumatic brain injury (TBI) is the leading cause of morbidity and mortality worldwide.
Although TBI leads to mechanical damage during initial impact, secondary damage also …

Temporomandibular joint disorder (TMD) is associated with pain in the joint
(temporomandibular joint, TMJ) and muscles involved in mastication. TMD pain dissipates …

Progesterone has been shown to exert a wide range of remarkable protective actions in
experimental models of central nervous system injury or disease. However, the intimate …

Gastrointestinal symptoms appear in Parkinson's disease patients many years before motor
symptoms, suggesting the implication of dopaminergic neurones of the gut myenteric plexus …

Severe traumatic brain injury (TBI) activates a robust systemic response that involves
inflammatory and other factors, including estradiol (E2), associated with increased deaths …

In response to stressor exposure, expression of the inflammatory cytokine interleukin-1β (IL-
1) is increased within the paraventricular nucleus of the hypothalamus (PVN). Surgical …

Astrocytes play many distinct roles in the nervous system providing structural support for
neurons and maintaining blood-brain barrier integrity. Steroid hormones exhibit a broad …

Objective The objective of this meta-analysis was to assess the efficacy of progesterone
(PG) at 1.0 mg kg− 1 once every 12 h for 5 consecutive days in patients with moderate-to …

Objective: The objective of this meta-analysis is to assess the efficacy and safety of
progesterone (PG) for traumatic brain injury (TBI). Methods: The databases Cochrane …