Renal disease is the common denominator of a number of underlying disease conditions,
whose prevalence has been dramatically increasing over the last two decades. Two aspects …

Idiopathic membranous nephropathy (IMN) is one of the main types of chronic kidney
disease in adults and one of the most common causes of end-stage renal disease. In recent …

A subset of individuals with type 1 diabetes will develop diabetic kidney disease (DKD).
DKD is heritable and large-scale genome-wide association studies have begun to identify …

The SS (Dahl salt sensitive) rat is an established model of hypertension and renal damage
that is accompanied with immune system activation in response to a high-salt diet …

Metabolite, also known as intermediate metabolite, refers to substances produced or
consumed in the metabolic processes. There are growing evidences that metabolites play …

Background Primary glomerulonephritis (GN) is the leading cause of chronic kidney disease
(CKD) and frequently progresses into end stage renal diseases (ESRDs). Shorter leukocyte …

Diabetes mellitus (DM) is a chronic multisystem disease. Diabetic nephropathy (DN) is one
of its significant microvascular complications, associated with increased morbidity and …

Membranous nephropathy (MN), a common pathological type of adult nephrotic syndrome,
is an antibody-mediated kidney disease. It is widely accepted now that MN is an immune …

Diabetes-associated chronic kidney disease is a pandemic issue. Despite the global
increase in the number of individuals with this chronic condition together with increasing …

DOCTOR OF PHILOSOPHY Next Generation Sequencing and Genome-Wide Association Studies
to Identify Mitochondrial Genomic Features Page 1 DOCTOR OF PHILOSOPHY Next Generation …