[HTML][HTML] Emerging concepts and technologies in vaccine development
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …
by pathogens, there are still known diseases and emerging pathogens for which the …
[HTML][HTML] Toward precision adjuvants: optimizing science and safety
E Nanishi, DJ Dowling, O Levy - Current opinion in pediatrics, 2020 - journals.lww.com
Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics
Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics Log …
Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics Log …
Mapping functional humoral correlates of protection against malaria challenge following RTS, S/AS01 vaccination
TJ Suscovich, JK Fallon, J Das, AR Demas… - Science translational …, 2020 - science.org
Vaccine development has the potential to be accelerated by coupling tools such as systems
immunology analyses and controlled human infection models to define the protective …
immunology analyses and controlled human infection models to define the protective …
[HTML][HTML] Host-malaria parasite interactions and impacts on mutual evolution
X Su, C Zhang, DA Joy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …
worldwide. Malaria parasites have been associated with their hosts for millions of years …
Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria
DK Raj, A Das Mohapatra, A Jnawali, J Zuromski… - Nature, 2020 - nature.com
Malaria caused by Plasmodium falciparum remains the leading single-agent cause of
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …
Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs
The circumsporozoite protein of the human malaria parasite Plasmodium falciparum
(PfCSP) is the main target of antibodies that prevent the infection and disease, as shown in …
(PfCSP) is the main target of antibodies that prevent the infection and disease, as shown in …
[HTML][HTML] Challenges of developing novel vaccines with particular global health importance
PM Heaton - Frontiers in immunology, 2020 - frontiersin.org
Six of the top ten leading causes of death in low resource settings could potentially be
prevented by vaccination. Development of vaccines for individuals in these populations is …
prevented by vaccination. Development of vaccines for individuals in these populations is …
[HTML][HTML] Plasmodium falciparum pre-erythrocytic stage vaccine development
J Molina-Franky, L Cuy-Chaparro, A Camargo… - Malaria journal, 2020 - Springer
Worldwide strategies between 2010 and 2017 aimed at controlling malarial parasites
(mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence …
(mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence …
[HTML][HTML] Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy
W Zhang, L Xu, HB Park, J Hwang, M Kwak… - Nature …, 2020 - nature.com
Induction of antigen-specific immune activation by the maturation of dendritic cells (DCs) is a
strategy used for cancer immunotherapy. In this study, we find that FimH, which is an …
strategy used for cancer immunotherapy. In this study, we find that FimH, which is an …