Abstract Purpose of Review To present a comprehensive overview regarding criteria,
epidemiology, and controversies that have arisen in the literature about the existence and …

Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …

Conclusions This study demonstrates that E. multilocularis can induce T‐cell exhaustion
through inhibitory receptor TIGIT, and that blocking this checkpoint may reverse the …

Abstract Objective Canonical Wnt/β-catenin signaling is a well-studied endogenous
regulator of mesenchymal cell fate determination, promoting osteoblastogenesis and …

Brown adipose tissue (BAT) is highly metabolically active tissue that dissipates energy via
UCP1 as heat, and BAT mass is correlated negatively with obesity. The presence of …

Obesity-associated metabolic illnesses are increasing at an alarming rate in Asian countries.
A common feature observed in the Asian population is a higher incidence of abdominal …

Sex differences in diseases involving oxidative and proteolytic stress are common, including
greater ischemic heart disease, Parkinson disease and stroke in men, and greater …

Overnutrition results in adiposity and chronic inflammation with expansion of white adipose
tissue (WAT). However, genetic factors controlling fat mass and adiposity remain largely …

Simple Summary According to the tail types, sheep can be briefly classified into three groups
(fat-tailed, fat-rumped, and thin-tailed sheep). In this study, we used these three typical …

Activity-based protein profiling (ABPP) has been used extensively to discover and optimize
selective inhibitors of enzymes. Here, we show that ABPP can also be implemented to …