Cerebral small vessel disease

J Litak, M Mazurek, B Kulesza, P Szmygin… - International journal of …, 2020 - mdpi.com
Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders
with different pathological backgrounds. The advanced vasculature net of cerebral vessels …

Blood pressure variability and cerebral small vessel disease: a systematic review and meta-analysis of population-based cohorts

Y Ma, A Song, A Viswanathan, D Blacker, MW Vernooij… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—Blood pressure (BP) variability may increase the risk of stroke
and dementia. It remains inconclusive whether BP variability is associated with cerebral …

Hippocampal vascular reserve associated with cognitive performance and hippocampal volume

V Perosa, A Priester, G Ziegler, A Cardenas-Blanco… - Brain, 2020 - academic.oup.com
Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the
hippocampal region, yet little is known about the relationship between the richness of …

Global burden of small vessel disease–related brain changes on MRI predicts cognitive and functional decline

H Jokinen, J Koikkalainen, HM Laakso, S Melkas… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—Cerebral small vessel disease is characterized by a wide range
of focal and global brain changes. We used a magnetic resonance imaging segmentation …

[HTML][HTML] Clinical relevance of cerebral small vessel diseases

M Pasi, C Cordonnier - Stroke, 2020 - journals.lww.com
Until recent years, cerebral small vessel disease (SVD) has drawn little attention mostly
because small cerebral arteries were difficult to observe in imaging and in vivo studies …

Association between immunosuppressive treatment and outcomes of cerebral amyloid angiopathy–related inflammation

RW Regenhardt, JM Thon, AS Das, OR Thon… - JAMA …, 2020 - jamanetwork.com
Importance Cerebral amyloid angiopathy–related inflammation (CAA-ri), a distinct subtype of
cerebral amyloid angiopathy, is characterized by an autoimmune reaction to …

New treatment approaches to modify the course of cerebral small vessel diseases

EE Smith, HS Markus - Stroke, 2020 - Am Heart Assoc
Smith and Markus Cerebral Small Vessel Disease Trials 39 dysmetabolism, and glucose
dysregulation that are the primary targets for current ischemic stroke prevention. As an …

Dynamic regional brain atrophy rates in the first year after ischemic stroke

A Brodtmann, MS Khlif, N Egorova, M Veldsman… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Brain atrophy can be regarded as an end-organ effect of
cumulative cardiovascular risk factors. Accelerated brain atrophy is described following …

Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities

NJ Armstrong, KA Mather, M Sargurupremraj, MJ Knol… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Periventricular white matter hyperintensities (WMH; PVWMH) and
deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in …

[HTML][HTML] Cholinergic white matter pathways make a stronger contribution to attention and memory in normal aging than cerebrovascular health and nucleus basalis of …

M Nemy, N Cedres, MJ Grothe, JS Muehlboeck… - Neuroimage, 2020 - Elsevier
The integrity of the cholinergic system plays a central role in cognitive decline both in normal
aging and neurological disorders including Alzheimer's disease and vascular cognitive …