Nanoparticle-based therapeutic approach for diabetic wound healing

H Ezhilarasu, D Vishalli, ST Dheen, BH Bay… - Nanomaterials, 2020 - mdpi.com
Diabetes mellitus (DM) is a common endocrine disease characterized by a state of
hyperglycemia (higher level of glucose in the blood than usual). DM and its complications …

The impact of psychological stress on mast cells

TC Theoharides - Annals of Allergy, Asthma & Immunology, 2020 - Elsevier
Objective Atopic diseases worsen with psychological stress, but how stress contributes to
their pathogenesis is still not clear. We review the evidence supporting the premise that …

[HTML][HTML] Topical application of a mast cell stabilizer improves impaired diabetic wound healing

A Tellechea, S Bai, S Dangwal, G Theocharidis… - Journal of Investigative …, 2020 - Elsevier
Impaired wound healing in the diabetic foot is a major problem often leading to amputation.
Mast cells have been shown to regulate wound healing in diabetes. We developed an …

The five primary prostaglandins stimulate contractions and phasic activity of the urinary bladder urothelium, lamina propria and detrusor

Z Stromberga, R Chess-Williams, C Moro - BMC urology, 2020 - Springer
Background Inflammation is often associated with several bladder dysfunctions, including
overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/PBS). As such …

[HTML][HTML] Mast cell‑mediated neuroinflammation may have a role in attention deficit hyperactivity disorder

Y Song, M Lu, H Yuan, T Chen… - Experimental …, 2020 - … .spandidos-publications.com
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental and
behavioral disorder with a serious negative impact on the quality of life from childhood until …

Modeling a nociceptive neuro-immune synapse activated by ATP and 5-HT in meninges: novel clues on transduction of chemical signals into persistent or rhythmic …

A Suleimanova, M Talanov, O Gafurov… - Frontiers in Cellular …, 2020 - frontiersin.org
Extracellular ATP and serotonin (5-HT) are powerful triggers of nociceptive firing in the
meninges, a process supporting headache and whose cellular mechanisms are …

Histamine-mediated autocrine signaling in mesenteric perilymphatic mast cells

S Pal, OY Gasheva, DC Zawieja… - American Journal …, 2020 - journals.physiology.org
Lymphatic vessels play a critical role in mounting a proper immune response by trafficking
peripheral immune cells to draining lymph nodes. Mast cells (MCs) are well known for their …

Sargassum horneri as a Functional Food Ameliorated IgE/BSA-Induced Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice

EJ Han, HS Kim, KKA Sanjeewa, K Jung, Y Jee… - Marine drugs, 2020 - mdpi.com
Sargassum horneri (S. horneri), an edible brown alga, has been proposed as a functional
food with an improvement effect on abnormal skin immune responses. The present study …

Soybean meal allergenic protein degradation and gut health of piglets fed protease-supplemented diets

S Park, JW Lee, AJ Cowieson… - Journal of animal …, 2020 - academic.oup.com
Two experiments were conducted to determine the effects of protease supplementation on
degradation of soybean meal (SBM) allergenic proteins (glycinin and β-conglycinin) and gut …

Amyotrophic lateral sclerosis, neuroinflammation, and cromolyn

TC Theoharides, I Tsilioni - Clinical Therapeutics, 2020 - Elsevier
Amyotrophic lateral sclerosis (ALS) is an upper motor neuron disease with an unknown
pathogenesis and no effective treatment. A recent study found that treatment of a mouse …