Objective To perform a systematic review of the influence of sociobehavioural indicators of
cognitive reserve (CR) in the risk of schizophrenia, the clinical manifestations of the disease …

Abstract Treatment-resistant schizophrenia may be related to structural brain alterations.
However, the mechanisms underlying these changes remain unclear. The present study had …

Introduction Asenapine maleate (AM) is an atypical antipsychotic agent, that has been
widely prescribed for the management of schizoaffective disorders. However, the …

Cognitive impairments characterize individuals with schizophrenia, and are correlated to the
patients' functional outcome. The transcription factor Cyclic AMP-responsive element …

Background Blonanserin transdermal patch therapy is now available in Japan for the
treatment of schizophrenia and may provide several advantages over the tablet formulation …

The dopamine and glutamate hypotheses reflect only some of the pathophysiological
changes associated with schizophrenia. We have proposed a new “comprehensive …

MicroRNAs (miRNAs) have been investigated in neurodevelopmental and psychiatric
disorders including schizophrenia (SZ). Previous studies showed miRNAs dysregulation in …

Objective: Aripiprazole, a synthetic compound, obtained by chemical modification of the
structure of quinolinone is considered as an atypical antipsychotic drug. The present review …

The dopamine transporter is coded by the SLC6A3 gene and plays an important role in
regulation of the neurotransmitter dopamine. To detect the association between the SLC6A3 …

While antipsychotics (APs) could provide rapid relief of positive symptoms in psychotic
disorders, their usage is often associated with side effects, stigma and inconveniences. For …