Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

The need for sleep in the adolescent brain

A Galván - Trends in cognitive sciences, 2020 - cell.com
Sleep is a basic need. Mounting evidence suggests this is particularly true during
adolescence, a developmental period involving substantial changes in the brain regions …

Distinct subnetworks of the thalamic reticular nucleus

Y Li, VG Lopez-Huerta, X Adiconis, K Levandowski… - Nature, 2020 - nature.com
The thalamic reticular nucleus (TRN), the major source of thalamic inhibition, regulates
thalamocortical interactions that are critical for sensory processing, attention and cognition 1 …

Slow oscillation-spindle coupling predicts enhanced memory formation from childhood to adolescence

MA Hahn, D Heib, M Schabus, K Hoedlmoser… - elife, 2020 - elifesciences.org
Precise temporal coordination of slow oscillations (SO) and sleep spindles is a fundamental
mechanism of sleep-dependent memory consolidation. SO and spindle morphology …

[HTML][HTML] Obstructive sleep apnea and its treatment in aging: effects on Alzheimer's disease biomarkers, cognition, brain structure and neurophysiology

AE Mullins, K Kam, A Parekh, OM Bubu, RS Osorio… - Neurobiology of …, 2020 - Elsevier
Here we review the impact of obstructive sleep apnea (OSA) on biomarkers of Alzheimer's
disease (AD) pathogenesis, neuroanatomy, cognition and neurophysiology, and present the …

[HTML][HTML] A role for spindles in the onset of rapid eye movement sleep

M Bandarabadi, CG Herrera, TC Gent… - Nature …, 2020 - nature.com
Sleep spindle generation classically relies on an interplay between the thalamic reticular
nucleus (TRN), thalamo-cortical (TC) relay cells and cortico-thalamic (CT) feedback during …

Understanding the interplay of sleep and aging: Methodological challenges

BE Muehlroth, M Werkle‐Bergner - Psychophysiology, 2020 - Wiley Online Library
In quest of new avenues to explain, predict, and treat pathophysiological conditions during
aging, research on sleep and aging has flourished. Despite the great scientific potential to …

[HTML][HTML] Analyzing human sleep EEG: A methodological primer with code implementation

R Cox, J Fell - Sleep medicine reviews, 2020 - Elsevier
Recent years have witnessed a surge in human sleep electroencephalography (EEG)
studies, employing increasingly sophisticated analysis strategies to relate …

[HTML][HTML] Gender differences in adolescent sleep neurophysiology: a high-density sleep EEG study

A Markovic, M Kaess, L Tarokh - Scientific reports, 2020 - nature.com
During adolescence, differences between males and females in physiology, behavior and
risk for psychopathology are accentuated. The goal of the current study was to examine …

Sleep electroencephalography and brain maturation: developmental trajectories and the relation with cognitive functioning

M Gorgoni, A D'Atri, S Scarpelli, F Reda, L De Gennaro - Sleep Medicine, 2020 - Elsevier
Sleep has a crucial role in brain functioning and cognition, and several sleep
electroencephalography (EEG) hallmarks are associated with intellectual abilities, neural …