Activating killer cell immunoglobulin‐like receptors: detection, function and therapeutic use

MD Blunt, SI Khakoo - International Journal of Immunogenetics, 2020 - Wiley Online Library
Killer cell immunoglobulin‐like receptors (KIRs) have a central role in the control of natural
killer (NK) cell function. The functions of the activating KIRs, as compared to those of the …

Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis

AL Hanson… - PLoS …, 2020 - journals.plos.org
The killer immunoglobulin-like receptors (KIRs), found predominantly on the surface of
natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating …

Killer‐cell immunoglobulin‐like receptor assessment algorithms in haemopoietic progenitor cell transplantation: current perspectives and future opportunities

PA Wright - HLA, 2020 - Wiley Online Library
Natural killer cells preferentially target and kill malignant and virally infected cells. Both
these properties present compelling clinical utility in the field of haemopoietic progenitor cell …

Regulation of NK-cell function by HLA class II

A Niehrs, M Altfeld - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
Natural Killer (NK) cells were initially described as part of the innate immune system and
characterized by their ability to lyse malignant and virus-infected cells. The cytolytic function …

Phenotypic and functional evaluation of NK Cells in men who have sex with men at high risk of HIV-1 infection from Medellin

L Flórez Álvarez - 2020 - bibliotecadigital.udea.edu.co
Introduction: HIV exposed seronegative (HESN), are individuals that remain seronegative
despite repeated exposure to HIV. Since the first reports of HIV resistance in humans in …

Mechanisms of Immune Control in HIV-1 Virus Controllers

TE Nyanhete - 2020 - search.proquest.com
There is a lack of a clear understanding of what constitutes a potent natural immune
response capable of mediating post-infection protection in an HIV-1 infection setting. Thus …

Cellular Determinants of the Natural Killer Cell Response to Viral Infections

CDS Albelda - 2020 - search.proquest.com
Natural killer (NK) cells are innate lymphocytes that play a critical role in controlling viral
infections, coordinating the response of innate and adaptive immune systems. They also …

[PDF][PDF] Recognition of viral peptides by inhibitory and activating killer immunoglobulin-like receptors

LY Bastidas Legarda - 2020 - eprints.soton.ac.uk
Background and Aim: Natural killer (NK) cells are lymphocytes from the innate immunity
critical in the control of viral infections. NK cell functions against viruses are largely regulated …

Use of c-terminally extended peptides to disrupt inhibitor nk cell receptor interactions with mhc i

D Zajonc, B Peters, SG Remesh, Y Ge - US Patent App. 16/348,839, 2020 - Google Patents
US20200216492A1 - Use of c-terminally extended peptides to disrupt inhibitor nk cell
receptor interactions with mhc i - Google Patents US20200216492A1 - Use of c-terminally …