Hematopoiesis has long served as a paradigm of stem cell biology and tissue homeostasis.
In the past decade, the genomics revolution has ushered in powerful new methods for …

Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …

The identification of disease alleles underlying human autoinflammatory diseases can
provide important insights into the mechanisms that maintain neutrophil homeostasis. Here …

Genome-wide association studies (GWAS) have identified thousands of genetic variants
associated with a range of human diseases and traits. However, understanding the …

Polygenic scores (PGSs) for blood cell traits can be constructed using summary statistics
from genome-wide association studies. As the selection of variants and the modelling of …

Exploring the genetic basis of blood cell traits | Nature Reviews Genetics Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

Importance Biomarkers for the early detection of Parkinson's disease (PD) are needed.
Patients with PD display differences in peripheral blood biomarkers of immune function …

Motivation Whole-genome DNA sequencing (WGS) enables the discovery of non-coding
variants, but tools are lacking to prioritize the subset that functionally impacts human …

While humans share most of their genetic code with one another, small differences in the
DNA can have an impact on an individual's risk of disease. Common genetic variants exert …

Low lymphocyte count is a risk factor for Parkinson’s disease Page 1 1 Low lymphocyte count is
a risk factor for Parkinson’s disease Melanie P Jensen (MBBS)*1, Benjamin Meir Jacobs …