Multisystem inflammatory syndrome in children (MIS-C), a post-viral myocarditis and systemic vasculitis—a critical review of its pathogenesis and treatment

JC McMurray, JW May, MW Cunningham… - Frontiers in …, 2020 - frontiersin.org
MIS-C is a newly defined post-viral myocarditis and inflammatory vasculopathy of children
following COVID-19 infection. This review summarizes the literature on diagnosis …

Efforts at COVID-19 vaccine development: challenges and successes

A Haque, AB Pant - Vaccines, 2020 - mdpi.com
The rapid spread of SARS-CoV-2, the new coronavirus (CoV), throughout the globe poses a
daunting public health emergency. Different preventive efforts have been undertaken in …

[HTML][HTML] SARS-CoV-2 viral load predicts mortality in patients with and without cancer who are hospitalized with COVID-19

LF Westblade, G Brar, LC Pinheiro, D Paidoussis… - Cancer cell, 2020 - cell.com
Patients with cancer may be at increased risk of severe coronavirus disease 2019 (COVID-
19), but the role of viral load on this risk is unknown. We measured SARS-CoV-2 viral load …

Rapid isothermal amplification and portable detection system for SARS-CoV-2

A Ganguli, A Mostafa, J Berger… - Proceedings of the …, 2020 - National Acad Sciences
The COVID-19 pandemic provides an urgent example where a gap exists between
availability of state-of-the-art diagnostics and current needs. As assay protocols and primer …

Model calculations of aerosol transmission and infection risk of COVID-19 in indoor environments

J Lelieveld, F Helleis, S Borrmann, Y Cheng… - International Journal of …, 2020 - mdpi.com
The role of aerosolized SARS-CoV-2 viruses in airborne transmission of COVID-19 has
been debated. The aerosols are transmitted through breathing and vocalization by infectious …

Controlled randomized clinical trial on using Ivermectin with Doxycycline for treating COVID-19 patients in Baghdad, Iraq

HA Hashim, MF Maulood, AM Rasheed, DF Fatak… - MedRxiv, 2020 - medrxiv.org
Objectives COVID-19 patients suffer from the lack of curative therapy. Hence, there is an
urgent need to try repurposed old drugs on COVID-19. Methods Randomized controlled …

Clinical evaluation of BD Veritor SARS-CoV-2 point-of-care test performance compared to PCR-based testing and versus the Sofia 2 SARS Antigen point-of-care test

S Young, SN Taylor, CL Cammarata… - Journal of clinical …, 2020 - Am Soc Microbiol
The clinical performance of the BD Veritor System for Rapid Detection of SARS-CoV-2
nucleocapsid antigen (Veritor), a chromatographic immunoassay used for SARS-CoV-2 …

Can air-conditioning systems contribute to the spread of SARS/MERS/COVID-19 infection? Insights from a rapid review of the literature

F Chirico, A Sacco, NL Bragazzi… - International journal of …, 2020 - mdpi.com
The airborne transmission of SARS-CoV-2 is still debated. The aim of this rapid review is to
evaluate the COVID-19 risk associated with the presence of air-conditioning systems …

Evaluation of the accuracy, ease of use and limit of detection of novel, rapid, antigen-detecting point-of-care diagnostics for SARS-CoV-2

LJ Krüger, M Gaeddert, L Koeppel, LE Brümmer… - medRxiv, 2020 - medrxiv.org
Background Reliable point-of-care (POC) diagnostics not requiring laboratory infrastructure
could be a game changer in the COVID-19 pandemic, particularly in the Global South. We …

Manipulation of ACE2 expression in COVID-19

F Chaudhry, S Lavandero, X Xie, B Sabharwal… - Open …, 2020 - openheart.bmj.com
SARS-CoV-2 is the virus responsible for the ongoing COVID-19 outbreak. The virus uses
ACE2 receptor for viral entry. ACE2 is part of the counter-regulatory renin-angiotensin …