The protective effects of peroxisome proliferator-activated receptor gamma in cerebral ischemia-reperfusion injury

Y Ding, J Kang, S Liu, Y Xu, B Shao - Frontiers in Neurology, 2020 - frontiersin.org
Cerebral ischemia-reperfusion injury (CI/RI) is a complex pathological process that often
occurs secondary to trauma, surgery, and shock. Peroxisome proliferator activated receptor …

The interactions between cancer stem cells and the innate interferon signaling pathway

L Martin-Hijano, B Sainz Jr - Frontiers in Immunology, 2020 - frontiersin.org
Interferons (IFNs) form a family of cytokines with pleiotropic effects that modulate the immune
response against multiple challenges like viral infections, autoimmune diseases, and …

Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia

Y Wada, M Maekawa, T Ohnishi, S Balan… - …, 2020 - thelancet.com
Background The pathophysiology of schizophrenia, a major psychiatric disorder, remains
elusive. In this study, the role of peroxisome proliferator-activated receptor (PPAR)/retinoid X …

Oridonin is an antidepressant molecule working through the PPAR-γ/AMPA receptor signaling pathway

P Liu, J Du - Biochemical Pharmacology, 2020 - Elsevier
Oridonin is a diterpene compound that regulates the activity of PPAR-γ (peroxisome
proliferator-activated receptor gamma) transcription factor. Cumulative evidence indicates …

Aqueous extract of pomegranate enriched in ellagitannins prevents anxiety-like behavior and metabolic changes induced by cafeteria diet in an animal model of …

EM Estrada-Camarena, C López-Rubalcava… - Neurochemistry …, 2020 - Elsevier
Women around menopause are vulnerable to present psychiatric and metabolic disorders;
thus, therapies that contribute to treat both pathologies are required. Previous reports …

Sleep profile during fasting in PPAR-alpha knockout mice

Y Kondo, S Chikahisa, T Shiuchi, N Shimizu… - Physiology & …, 2020 - Elsevier
Peroxisome proliferator-activated receptor alpha (PPARα) is a transcription factor that
belongs to the nuclear receptor family and plays an important role in regulating gene …

Steroid receptor RNA activator affects the development of poststroke depression by regulating the peroxisome proliferator-activated receptor γ signaling pathway

B Jiang, H Wang, H Xu - Neuroreport, 2020 - journals.lww.com
The long noncoding RNA, steroid receptor RNA activator (SRA), has been reported to be
involved in the development of many types of disease in humans. The aim of this study was …