Epidemiology of frailty in older people

S Rohrmann - Frailty and cardiovascular diseases: Research into an …, 2020 - Springer
Frailty is a complex of symptoms that is characterized by impaired stress tolerance due to a
decline in the functionality of different organs. Due to its multifactorial aetiology, several …

Association of inflammatory mediators with frailty status in older adults: results from a systematic review and meta-analysis

D Marcos-Pérez, M Sánchez-Flores, S Proietti… - GeroScience, 2020 - Springer
Frailty is a geriatric syndrome defined as a status of extreme vulnerability to stressors,
leading to a higher risk of negative health-related outcomes.“Inflammaging”, an age-related …

The neutrophil: constant defender and first responder

N Fine, N Tasevski, CA McCulloch… - Frontiers in …, 2020 - frontiersin.org
The role of polymorphonuclear neutrophils (PMNs) in biology is often recognized during
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …

Inflammatory biomarkers of frailty

M Vatic, S von Haehling, N Ebner - Experimental Gerontology, 2020 - Elsevier
Frailty is a functional term that describes a decline in physiological functions that leads to
dependency, vulnerability to stressors, high risk for adverse health outcomes, increased risk …

Frailty in rheumatic diseases

F Motta, A Sica, C Selmi - Frontiers in immunology, 2020 - frontiersin.org
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of
several systems, leading to increased vulnerability and adverse health outcomes. While …

[HTML][HTML] Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models

M Álvarez-Satta, A Berna-Erro… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Frailty represents a state of vulnerability and increases the risk of negative health outcomes,
which is becoming an important public health problem. Over recent years, multiple …

Prehabilitation for the frailty syndrome: improving outcomes for our most vulnerable patients

CM Norris, JCT Close - Anesthesia & Analgesia, 2020 - journals.lww.com
Anesthetists are increasingly faced with the challenge of delivering perioperative care to frail
older people. Patients with frailty undergoing surgical intervention are at a significantly …

Prevalence and factors associated with frailty in hospitalized older patients

S Hammami, A Zarrouk, C Piron, I Almas, N Sakly… - BMC geriatrics, 2020 - Springer
Background Frailty is a multidimensional syndrome that leads to an increase of an age-
related disorder of several physiological systems, and cognitive abilities decline. The aim of …

Frailty is independently associated with mortality in 11 001 patients with inflammatory bowel diseases

B Kochar, W Cai, A Cagan… - Alimentary …, 2020 - Wiley Online Library
Background The prevalence of older adults with inflammatory bowel diseases (IBD) is
increasing. Frailty is an important predictor of outcomes in many chronic disease states. The …

Protein intake and transitions between frailty states and to death in very old adults: the Newcastle 85+ study

N Mendonça, A Kingston, A Granic, C Jagger - Age and ageing, 2020 - academic.oup.com
Objectives To examine the association of protein intake with frailty progression in very old
adults. Design The Newcastle 85+ study, a prospective longitudinal study of people aged 85 …