Lipids and Alzheimer's disease

YC Kao, PC Ho, YK Tu, IM Jou, KJ Tsai - International journal of molecular …, 2020 - mdpi.com
Lipids, as the basic component of cell membranes, play an important role in human health
as well as brain function. The brain is highly enriched in lipids, and disruption of lipid …

Challenging microalgal vitamins for human health

A Del Mondo, A Smerilli, E Sané, C Sansone… - Microbial Cell …, 2020 - Springer
Background Vitamins' deficiency in humans is an important threat worldwide and requires
solutions. In the concept of natural biofactory for bioactive compounds production …

Healthy brain, healthy life: a review of diet and exercise interventions to promote brain health and reduce Alzheimer's disease risk

BJ Baranowski, DM Marko, RK Fenech… - Applied Physiology …, 2020 - cdnsciencepub.com
With the world's population aging at a rapid rate, the prevalence of Alzheimer's disease (AD)
has significantly increased. These statistics are alarming given recent evidence that a third …

Inflammation in neurological disorders: the thin boundary between brain and periphery

C Cervellati, A Trentini, A Pecorelli… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Accumulating evidence suggests that inflammation is a major contributor in the
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …

Mitochondrial dysfunctions: a red thread across neurodegenerative diseases

S Stanga, A Caretto, M Boido, A Vercelli - International journal of …, 2020 - mdpi.com
Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

Walnut (Juglans regia L.) Septum: Assessment of Bioactive Molecules and In Vitro Biological Effects

ME Rusu, I Fizesan, A Pop, A Mocan, AM Gheldiu… - Molecules, 2020 - mdpi.com
Walnut (Juglans regia L.) septum represents an interesting bioactive compound source by-
product. In our study, a rich phenolic walnut septum extract, previously selected, was further …

Targeting oxidative stress for disease prevention and therapy: Where do we stand, and where do we go from here

C Vassalle, M Maltinti, L Sabatino - Molecules, 2020 - mdpi.com
Oxidative stress (OxS) is one of the main processes related to aging and a common
denominator of many different chronic/degenerative diseases (eg, cardiovascular and …

The pleiotropic role of p53 in functional/dysfunctional neurons: Focus on pathogenesis and diagnosis of Alzheimer's disease

G Abate, GB Frisoni, JC Bourdon, S Piccirella… - Alzheimer's Research & …, 2020 - Springer
Background Understanding the earliest pathophysiological changes of Alzheimer's disease
(AD) may aid in the search for timely diagnostic biomarkers and effective disease-modifying …

Association of antioxidant vitamins A, C, E and carotenoids with cognitive performance over time: A cohort study of middle-aged adults

MA Beydoun, JA Canas, MT Fanelli-Kuczmarski… - Nutrients, 2020 - mdpi.com
Carotenoids may strengthen the association of antioxidant vitamins A, C, and E with
favorable cognitive outcomes over time, though a few prospective studies have examined …

Simultaneous determination of vitamin E and vitamin K in food supplements using adsorptive stripping square-wave voltammetry at glassy carbon electrode

G Kastrati, G Jashari, M Sýs, B Švecová, T Arbneshi… - Applied Sciences, 2020 - mdpi.com
A new voltammetric method for the simultaneous determination of vitamin E and vitamin K
present in different types of commercially available food supplements has been developed …