A field guide to eukaryotic transposable elements

JN Wells, C Feschotte - Annual review of genetics, 2020 - annualreviews.org
Transposable elements (TEs) are mobile DNA sequences that propagate within genomes.
Through diverse invasion strategies, TEs have come to occupy a substantial fraction of …

Beyond the RNA-dependent function of LncRNA genes

T Ali, P Grote - Elife, 2020 - elifesciences.org
While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last
decade, the focus regarding their mechanisms of action has been primarily on the RNA …

RepeatModeler2 for automated genomic discovery of transposable element families

JM Flynn, R Hubley, C Goubert… - Proceedings of the …, 2020 - National Acad Sciences
The accelerating pace of genome sequencing throughout the tree of life is driving the need
for improved unsupervised annotation of genome components such as transposable …

Silencing and transcriptional regulation of endogenous retroviruses: an overview

FK Geis, SP Goff - Viruses, 2020 - mdpi.com
Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …

Review on the computational genome annotation of sequences obtained by next-generation sequencing

GF Ejigu, J Jung - Biology, 2020 - mdpi.com
Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

Genetics and genomics of moso bamboo (Phyllostachys edulis): Current status, future challenges, and biotechnological opportunities toward a sustainable bamboo …

M Ramakrishnan, K Yrjälä, KK Vinod… - Food and Energy …, 2020 - Wiley Online Library
Sustainable goals for contemporary world seek viable solutions for interconnected
challenges, particularly in the fields of food and energy security and climate change. We …

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

S Bi, Z Liu, Z Wu, Z Wang, X Liu, S Wang, J Ren… - Protein & …, 2020 - academic.oup.com
SIRT7, a sirtuin family member implicated in aging and disease, is a regulator of metabolism
and stress responses. It remains elusive how human somatic stem cell populations might be …

Structural basis of seamless excision and specific targeting by piggyBac transposase

Q Chen, W Luo, RA Veach, AB Hickman… - Nature …, 2020 - nature.com
The piggyBac DNA transposon is used widely in genome engineering applications. Unlike
other transposons, its excision site can be precisely repaired without leaving footprints and it …

Horizontal transfer and evolution of transposable elements in vertebrates

HH Zhang, J Peccoud, MRX Xu, XG Zhang… - Nature …, 2020 - nature.com
Horizontal transfer of transposable elements (HTT) is an important process shaping
eukaryote genomes, yet very few studies have quantified this phenomenon on a large scale …

The evolutionary significance of RNAi in the fungal kingdom

C Lax, G Tahiri, JA Patiño-Medina… - International Journal of …, 2020 - mdpi.com
RNA interference (RNAi) was discovered at the end of last millennium, changing the way
scientists understood regulation of gene expression. Within the following two decades, a …