Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

Simple Summary Ewing sarcoma is a highly aggressive malignancy affecting primarily
children and adolescents. It is the second most common bone sarcoma among children …

Background Previous studies have noted the incidence of radiation-induced sarcomas (RIS)
but have not investigated the relative risk (RR) of developing RIS based on primary tumor …

Simple Summary Currently survival from retinoblastoma exceeds 95% in high-
income/resource countries. Life expectancy within the heritable retinoblastoma population is …

Background Therapy for a first primary neoplasm (FPN) in childhood with high doses of
ionizing radiation is an established risk factor for second primary neoplasms (SPN). An …

Objective To develop and internally validate a clinical predictive tool to assess the likelihood
that a young cancer patient will experience diminished ovarian reserve (DOR) after …

Simple Summary Osteosarcoma is highly variable and heterogeneous, which is one of the
reasons for its resistance to treatment. Because osteosarcoma is defined by abnormal bone …

Purpose and methods Sarcomas of the sellar region are uncommon and unexpected
tumors. Here, we review the cases reported in literature via a systematic search. Results …

Sarcomas are a group of rare malignant neoplasms of mesenchymal origin which may occur
in skeletal and extraskeletal tissue, including muscles, tendons, fat, synovium, fibrous tissue …

Bone and soft tissue sarcomas collectively make up 12% of all pediatric malignancies. While
there have been significant improvements in treatment for these sarcomas, mortality and …