The role of AMPK in regulation of Na+,K+-ATPase in skeletal muscle: does the gauge always plug the sink?

S Pirkmajer, M Petrič, AV Chibalin - Journal of Muscle Research and Cell …, 2021 - Springer
AMP-activated protein kinase (AMPK) is a cellular energy gauge and a major regulator of
cellular energy homeostasis. Once activated, AMPK stimulates nutrient uptake and the ATP …

[HTML][HTML] Na, K-ATPase as a target for endogenous cardiotonic steroids: What's the evidence?

SN Orlov, AM Tverskoi, SV Sidorenko… - Genes & …, 2021 - Elsevier
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin,
mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less …

Apoptosis resistance of senescent cells is an intrinsic barrier for senolysis induced by cardiac glycosides

PI Deryabin, AN Shatrova, AV Borodkina - Cellular and Molecular Life …, 2021 - Springer
Targeted elimination of senescent cells, senolysis, is one of the core trends in the anti-aging
therapy. Cardiac glycosides were recently proved to be a broad-spectrum senolytics. Here …

Depth of the steroid core location determines the mode of Na, K-ATPase inhibition by cardiotonic steroids

AM Tverskoi, YM Poluektov, EA Klimanova… - International Journal of …, 2021 - mdpi.com
Cardiotonic steroids (CTSs) are specific inhibitors of Na, K-ATPase (NKA). They induce
diverse physiological effects and were investigated as potential drugs in heart diseases …

Contribution of Monovalent (Na+ and K+) and Divalent (Ca2+) Ions to the Mechanisms of Synaptic Plasticity

LV Smolyaninova, AA Shiyan, GV Maksimov… - … ), Supplement Series A …, 2021 - Springer
The review presents the mechanisms of participation of ions (Na+, K+, and Ca 2+) in the
processes of synaptic plasticity in the postsynaptic neuron during long-term potentiation and …