Control of RNA stability in immunity

S Akira, K Maeda - Annual review of immunology, 2021 - annualreviews.org
Posttranscriptional control of mRNA regulates various biological processes, including
inflammatory and immune responses. RNA-binding proteins (RBPs) bind cis-regulatory …

[HTML][HTML] Targeting the RNA-binding protein HuR alleviates neuroinflammation in experimental autoimmune encephalomyelitis: Potential therapy for multiple sclerosis

V Borgonetti, MD Sanna, L Lucarini, N Galeotti - Neurotherapeutics, 2021 - Elsevier
Multiple sclerosis (MS) is a chronic autoimmune inflammatory and neurodegenerative
disease of the central nervous system characterized by demyelination, axonal loss, and …

HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4+ T Cell Activation and Th17 Cell Differentiation

S Yu, M Tripod, U Atasoy, J Chen - Journal of Immunology …, 2021 - Wiley Online Library
After antigen and/or different cytokine stimulation, CD4+ T cells activated and differentiated
into distinct T helper (Th) cells via differential T cell signaling pathways. Transcriptional …

ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection

S Ni, Y Zhou, L Song, Y Chen, X Wang, X Du… - Communications …, 2021 - nature.com
Previous studies have shown that ELAVL1 plays multiple roles, but its overall biological
function remains ill-defined. Here we clearly demonstrated that zebrafish ELAVL1a was a …

Crosstalk between RNA‐Binding Proteins and Immune Microenvironment Revealed Two RBP Regulatory Patterns with Distinct Immunophenotypes in Periodontitis

L Xing, G Meng, T Chen, X Zhang… - Journal of Immunology …, 2021 - Wiley Online Library
Periodontitis is an inflammatory disease whose pathogenesis is closely related with
immunology. RNA‐binding proteins (RBPs) were found to play crucial roles in immunity …

[PDF][PDF] Einfluss RNA-bindender Proteine auf murine T-Zellen in der Tumortherapie

L Mallaun - 2021 - edoc.ub.uni-muenchen.de
Nach dem heutigen Stand der Wissenschaft ist das Immunsystem physiologischerweise in
der Lage, Krebszellen zu erkennen und zu eliminieren. Verschiedene, zum Teil noch …