[HTML][HTML] The first 12 months of COVID-19: a timeline of immunological insights

T Carvalho, F Krammer, A Iwasaki - Nature Reviews Immunology, 2021 - nature.com
Since the initial reports of a cluster of pneumonia cases of unidentified origin in Wuhan,
China, in December 2019, the novel coronavirus that causes this disease—severe acute …

[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

[HTML][HTML] Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

DS Khoury, D Cromer, A Reynaldi, TE Schlub… - Nature medicine, 2021 - nature.com
Predictive models of immune protection from COVID-19 are urgently needed to identify
correlates of protection to assist in the future deployment of vaccines. To address this, we …

Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia

Y Herishanu, I Avivi, A Aharon, G Shefer… - Blood, The Journal …, 2021 - ashpublications.org
Patients with chronic lymphocytic leukemia (CLL) have an increased risk for severe COVID-
19 disease and mortality. The goal of this study was to determine the efficacy of COVID-19 …

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

JM Dan, J Mateus, Y Kato, KM Hastie, ED Yu, CE Faliti… - Science, 2021 - science.org
INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …

[HTML][HTML] Immunity, endothelial injury and complement-induced coagulopathy in COVID-19

L Perico, A Benigni, F Casiraghi, LFP Ng… - Nature Reviews …, 2021 - nature.com
In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …

[HTML][HTML] Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

AK Wheatley, JA Juno, JJ Wang, KJ Selva… - Nature …, 2021 - nature.com
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …

[HTML][HTML] Functional SARS-CoV-2-specific immune memory persists after mild COVID-19

LB Rodda, J Netland, L Shehata, KB Pruner… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is causing a
global pandemic, and cases continue to rise. Most infected individuals experience mildly …

[HTML][HTML] Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection

D Cromer, JA Juno, D Khoury, A Reynaldi… - Nature Reviews …, 2021 - nature.com
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …

[HTML][HTML] Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells

I Schulien, J Kemming, V Oberhardt, K Wild… - Nature medicine, 2021 - nature.com
Emerging data indicate that SARS-CoV-2-specific CD8+ T cells targeting different viral
proteins are detectable in up to 70% of convalescent individuals,,,–. However, very little …