Temporal trend and attributable risk factors of stroke burden in China, 1990–2019: an analysis for the Global Burden of Disease Study 2019

Q Ma, R Li, L Wang, P Yin, Y Wang, C Yan… - The Lancet Public …, 2021 - thelancet.com
Background Understanding the temporal trend of the disease burden of stroke and its
attributable risk factors in China, especially at provincial levels, is important for effective …

Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis

MA Karalexi, CF Tagkas, G Markozannes… - Environmental …, 2021 - Elsevier
Despite the abundance of epidemiological evidence concerning the association between
pesticide exposure and adverse health outcomes including acute childhood leukemia (AL) …

Timeliness of diagnosis and treatment: the challenge of childhood cancers

CJR Mullen, RD Barr, EL Franco - British journal of cancer, 2021 - nature.com
Cancer represents an important cause of disease-related death in children worldwide.
Improved treatment and understanding of the ways in which cancer manifests has allowed …

Consensus Middle East and North Africa Registry on inborn errors of immunity

A Aghamohammadi, N Rezaei, R Yazdani… - Journal of clinical …, 2021 - Springer
Background Inborn errors of immunity (IEIs) are a heterogeneous group of genetic defects of
immunity, which cause high rates of morbidity and mortality mainly among children due to …

Nanotechnology-assisted microfluidic systems: from bench to bedside

N Rabiee, S Ahmadi, Y Fatahi, M Rabiee… - …, 2021 - Taylor & Francis
With significant advancements in research technologies, and an increasing global
population, microfluidic and nanofluidic systems (such as point-of-care, lab-on-a-chip, organ …

A systematic examination of burden of childhood cancers in 183 countries: estimates from GLOBOCAN 2018

R Sharma - European Journal of Cancer Care, 2021 - Wiley Online Library
Objective Childhood cancers are a significant cause of child deaths worldwide. This study
examines the burden of 33 childhood cancers in 183 countries. Methods The estimates of …

Fertility-related concerns and uncertainties in adolescent and young adult childhood cancer survivors

FA Jardim, LC Lopes-Junior… - Journal of Adolescent …, 2021 - liebertpub.com
Purpose: This study aimed to uncover the fertility-related concerns and uncertainties in
adolescent and young adult (AYA) childhood cancer survivors. Methods: In this qualitative …

Disease burden and attributable risk factors of respiratory infections in China from 1990 to 2019

Z Ruan, J Qi, ZM Qian, M Zhou, Y Yang… - The Lancet Regional …, 2021 - thelancet.com
Background There was lack of data on the burdens and trends of upper and lower
respiratory infections (URIs and LRIs) over the past three decades in China. Methods We …

Patient-derived bone marrow spheroids reveal leukemia-initiating cells supported by mesenchymal hypoxic niches in pediatric B-ALL

JC Balandrán, J Dávila-Velderrain… - Frontiers in …, 2021 - frontiersin.org
B-cell acute lymphoblastic leukemia (B-ALL) results from the expansion of malignant
lymphoid precursors within the bone marrow (BM), where hematopoietic niches and …

Neuroblastoma invasion strategies are regulated by the extracellular matrix

C Gavin, N Geerts, B Cavanagh, M Haynes… - Cancers, 2021 - mdpi.com
Simple Summary Paediatric cancer research in general and neuroblastoma, in particular,
has minimal preclinical models of metastasis. As 50% of primary neuroblastomas have …