Psoriasis is a chronic inflammatory disease characterised by sharply demarcated
erythematous and scaly skin lesions accompanied by systemic manifestations. Classified by …

The skin barrier is broadly composed of two elements—a physical barrier mostly localised in
the epidermis, and an immune barrier localised in both the dermis and epidermis. These two …

Psoriasis is a chronic and relapsing disorder with considerable negative effects on patients'
quality of life. The finer details associated with the molecular mechanism of psoriasis and its …

Background Hundreds of variants associated with atopic dermatitis (AD) and psoriasis, 2
common inflammatory skin disorders, have previously been discovered through genome …

Psoriasis is an autoimmune chronic inflammatory condition of skin affecting 125 million
populaces around the globe. It is implicated as a result of multifaceted phenomena involving …

Stratified epithelia such as the epidermis require coordinated regulation of stem and
progenitor cell proliferation, survival, and differentiation to maintain homeostasis. Integrin …

(1) Background: Understanding the function of circular RNAs (circRNAs), a class of
noncoding RNA, in psoriatic skin can provide important insights into the complex regulation …

Psoriasis is a complex, chronic inflammatory skin disease characterized by keratinocyte
hyperproliferation and a disordered immune response; however, its exact etiology remains …

Objective To identify the narrowband ultraviolet B (NB-UVB)-induced molecular mechanisms
that may account for their anti-inflammatory efficacy, gene expression and transcriptome …

Abstract CCHCR1 (Coiled-Coil alpha-Helical Rod 1), maps to chromosomal region 6p21. 3,
within the major psoriasis susceptibility locus PSORS1. CCHCR1 itself is a plausible …