Cannabidiol: pharmacology and therapeutic targets
SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …
Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview
Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational
and medicinal purposes. In many countries, cannabis‐based medicines have been …
and medicinal purposes. In many countries, cannabis‐based medicines have been …
Evidence for use of cannabinoids in mood disorders, anxiety disorders, and PTSD: a systematic review
CN Stanciu, MF Brunette, N Teja… - Psychiatric …, 2021 - Am Psychiatric Assoc
Objective: Two primary compounds of the cannabis plant (Cannabis sativa), delta-9-
tetrahydrocannabinol (THC) and cannabidiol (CBD), differentially and dose-dependently …
tetrahydrocannabinol (THC) and cannabidiol (CBD), differentially and dose-dependently …
The cannabinoid system and microglia in health and disease
SS Duffy, JP Hayes, NT Fiore, G Moalem-Taylor - Neuropharmacology, 2021 - Elsevier
Recent years have yielded significant advances in our understanding of microglia, the
immune cells of the central nervous system (CNS). Microglia are key players in CNS …
immune cells of the central nervous system (CNS). Microglia are key players in CNS …
[HTML][HTML] The short-term and long-term effects of cannabis on cognition: recent advances in the field
The aim of this review is to discuss the most recent evidence for the short-term and long-term
effects of cannabis on cognition. The evidence that cannabis intoxication is associated with …
effects of cannabis on cognition. The evidence that cannabis intoxication is associated with …
Neuropharmacological effects of the main phytocannabinoids: a narrative review
RG Dos Santos, JEC Hallak, JAS Crippa - … and neuropsychiatric disorders, 2021 - Springer
Cannabis can synthetize more than 400 compounds, including terpenes, flavonoids, and
more than 100 phytocannabinoids. The main phytocannabinoids are Δ-9 …
more than 100 phytocannabinoids. The main phytocannabinoids are Δ-9 …
Endocannabinoids, cannabinoids and the regulation of anxiety
Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety
often reported as a primary reason for use. Only recently has the specific role cannabinoids …
often reported as a primary reason for use. Only recently has the specific role cannabinoids …
[HTML][HTML] The impact of cannabidiol on human brain function: a systematic review
A Batalla, J Bos, A Postma, MG Bossong - Frontiers in pharmacology, 2021 - frontiersin.org
Background: Accumulating evidence suggests that the non-intoxicating cannabinoid
compound cannabidiol (CBD) may have antipsychotic and anxiolytic properties, and thus …
compound cannabidiol (CBD) may have antipsychotic and anxiolytic properties, and thus …
Cannabis and cognitive functioning: from acute to residual effects, from randomized controlled trials to prospective designs
In recent years, several jurisdictions have revised their regulation policy toward both medical
and recreational use of cannabis. These changes have elicited concerns regarding how …
and recreational use of cannabis. These changes have elicited concerns regarding how …
The Yin and Yang of Cannabis: a systematic review of human neuroimaging evidence of the differential effects of Δ9-tetrahydrocannabinol and cannabidiol
B Gunasekera, C Davies, R Martin-Santos… - Biological Psychiatry …, 2021 - Elsevier
Abstract Cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (THC) have been the most
investigated cannabinoids at the human and preclinical levels, although the neurobiological …
investigated cannabinoids at the human and preclinical levels, although the neurobiological …