Current concepts and advances in biomarkers of acute kidney injury

Y Wen, CR Parikh - Critical reviews in clinical laboratory sciences, 2021 - Taylor & Francis
Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Uromodulin: roles in health and disease

C Schaeffer, O Devuyst… - Annual review of …, 2021 - annualreviews.org
Uromodulin, a protein exclusively produced by the kidney, is the most abundant urinary
protein in physiological conditions. Already described several decades ago, uromodulin has …

Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease

B Ponte, MC Sadler, E Olinger, P Vollenweider… - Kidney international, 2021 - Elsevier
UMOD variants associated with higher levels of urinary uromodulin (uUMOD) increase the
risk of chronic kidney disease (CKD) and hypertension. However, uUMOD levels also reflect …

Serum uromodulin and decline of kidney function in older participants of the population-based KORA F4/FF4 study

C Then, HL Then, A Lechner, B Thorand… - Clinical Kidney …, 2021 - academic.oup.com
Background Uromodulin, a tissue-specific tubular glycoprotein, has recently emerged as a
promising biomarker for kidney function and tubular integrity. However, the association of …

[HTML][HTML] Combined use of serum uromodulin and eGFR to estimate mortality risk

B Yazdani, GE Delgado, H Scharnagl… - Frontiers in …, 2021 - frontiersin.org
Serum uromodulin (sUmod) shows a strong direct correlation with eGFR in patients with
impaired kidney function and an inverse association with mortality. However, there are …

Individual uromodulin serum concentration is independent of glomerular filtration rate in healthy kidney donors

D Enko, A Meinitzer, JE Scherberich… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives The mucoprotein uromodulin is considered to correlate with glomerular filtration
rates (GFR) in patients with chronic kidney disease (CKD). Here we investigated how serum …

Uromodulin–a new marker of kidney function?

C Holzmann-Littig, L Renders, D Steubl - Clinical Nephrology, 2021 - search.proquest.com
Sir,–Uromodulin, also known as Tamm-Horsfall-protein is an~ 95 kDa large molecule
exclusively produced in the ascending limb in the loop of Henle and in the distal tubule [1] …

Uromodulin as a potential candidate marker for predicting the course of chronic kidney disease

LD Denova - KIDNEYS, 2021 - kidneys.zaslavsky.com.ua
Uromodulin is a nephrospecific protein that is most common in normal urine. And although it
has been known for more than 70 years, the function of uromodulin remains unclear …

[PDF][PDF] Уромодулін як потенційний кандидат-маркер прогнозування перебігу хронічної хвороби нирок

ЛД Денова - Нирки, 2021 - kidneys.zaslavsky.com.ua
І хоча він відомий більше 70 років, функція уромодуліну залишається до кінця не ясною.
Уромодулін бере участь у регулюванні транспорту солей, захищає від інфекцій …

Serum Level of Uromodulin as an Early Predictor Marker of Kidney Disorders

SM El-Shebini, HA Essa, MIA Moaty… - … Macedonian Journal of …, 2021 - oamjms.eu
BACKGROUND: Metabolic diseases are known to be risk factors of kidney injury. The
glycoprotein Uromodulin Tamm-Horsfall protein is a biochemical marker specifically …