Toward overcoming treatment failure in rheumatoid arthritis

Z Wang, J Huang, D Xie, D He, A Lu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and
bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines …

Potential clinical biomarkers in rheumatoid arthritis with an omic approach

Y Puentes-Osorio, P Amariles, MÁ Calleja… - Autoimmunity …, 2021 - Springer
Objective To aid in the selection of the most suitable therapeutic option in patients with
diagnosis of rheumatoid arthritis according to the phase of disease, through the review of …

Influence of the FCGR2A rs1801274 and FCGR3A rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis

N Márquez Pete, MM Maldonado Montoro… - Journal of Personalized …, 2021 - mdpi.com
Abatacept (ABA) is an immunosuppressant indicated for treatment of rheumatoid arthritis
(RA). Effectiveness might be influenced by clinical RA variants and single-nucleotide …

COVID-19 infection and rheumatoid arthritis: mutual outburst cytokines and remedies

NM Elemam, AA Maghazachi… - Current Medical Research …, 2021 - Taylor & Francis
Abstract In March 2020, COVID-19 infection caused by SARS-CoV-2 has been declared to
be a global pandemic, where its complications, severity and mortality are reported to be due …

Novel COVID-19 phenotype definitions reveal phenotypically distinct patterns of genetic association and protective effects

GHL Roberts, R Partha, B Rhead, SC Knight, DS Park… - medRxiv, 2021 - medrxiv.org
INTRODUCTION PARAGRAPH Multiple large COVID-19 genome-wide association studies
(GWAS) have identified reproducible genetic associations indicating that some infection …

Influencia genética en la variabilidad de la respuesta al tratamiento con Abatacept en pacientes con artritis reumatoide

N Márquez Pete - 2021 - digibug.ugr.es
La Artritis reumatoide (AR) es una enfermedad autoinmune crónica de etiología compleja
en la que interviene factores sociodemográficos, ambientales y genéticos, cuya prevalencia …

Interleukin-6 receptor genetic variation and tocilizumab treatment response to COVID-19

AA Almarzooq - medRxiv, 2021 - medrxiv.org
ABSTRACT Interleukin-6 receptor (IL6R) stimulates the inflammatory pathways as part of the
acute-phase response to infection. Tocilizumab is a monoclonal antibody that inhibits both …

[PDF][PDF] Gene influencing in COVID-19 infection, disease severity and its Pharmacotherapy

S Sarkar, S Dasgupta, V Srivastava, S Sahoo… - Int J Cur Res Rev …, 2021 - researchgate.net
Current pandemic COVID-19 has severely affected the world, having a mortality rate ranging
from 1 to 10% which is different for many countries. The time interval from symptoms to …

[引用][C] Personalizovana medicina i COVID-19: značaj genomskog profilisanja pacijenata i bioinformatike

B Zukić, B Stanković, N Kotur - Trendovi u …, 2021 - Beograd: Institut za molekularnu …