Glucose transporter GLUT1 is a transmembrane protein responsible for the uptake of
glucose into the cells of many tissues through facilitative diffusion. Plasma membrane (PM) …

Nutrient supply and demand delineate cell behavior in health and disease. Mammalian cells
have developed multiple strategies to secure the necessary nutrients that fuel their …

Astroglial aerobic glycolysis, a process during which d-glucose is converted to l-lactate, a
brain fuel and signal, is regulated by the plasmalemmal receptors, including adrenergic …

The human glucose transporters GLUT1 and GLUT3 have a central role in glucose uptake
as canonical members of the Sugar Porter (SP) family. GLUT1 and GLUT3 share a fully …

Transmembrane proteins have critical biological functions and play a role in a multitude of
cellular processes including cell signaling, transport of molecules and ions across …

Rationale: Cancer cells rely on glucose metabolism for fulfilling their high energy demands.
We previously reported that monoethanolamine (Etn), an orally deliverable lipid formulation …

Cancer cells reprogram their metabolism to survive and grow. Small-molecule inhibitors
targeting cancer are useful for studying its metabolic pathways and functions and for …

Although recurrent cancers can become life threatening, little is known about the
intracellular events required for cancer recurrences. Due to this lack of mechanistic …

Background Steroid-induced osteonecrosis of the femoral head (SONFH) is a chronic and
crippling bone disease. This study aims to reveal novel diagnostic biomarkers of SONFH …

Gestational diabetes mellitus (GDM) is a disease with abnormal blood glucose for the first
time in gestation, and its main harm is vascular lesions, usually diabetic kidney damage. A …