Tumors are not only aggregates of malignant cells but also well-organized complex
ecosystems. The immunological components within tumors, termed the tumor immune …

Attributable to its late diagnosis, early metastasis, and poor prognosis, pancreatic cancer
remains one of the most lethal diseases worldwide. Unlike other solid tumors, pancreatic …

Sonodynamic therapy (SDT), which involves a combination of low-intensity ultrasound (US)
and a chemical sonosensitizer, has emerged as a promising minimally invasive and …

Sonodynamic therapy is considered as a minimally invasive method for pathogen
elimination and cancer therapy with high spatial and temporal accuracy. However …

Sonodynamic therapy (SDT) is a novel noninvasive therapeutic modality that combines low‐
intensity ultrasound and sonosensitizers. Versus photo‐mediated therapy, SDT has the …

Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

A hypoxic and acidic tumor microenvironment (TME) plays a significant role in cancer
development through complex cellular signaling networks, and it is thus challenging to …

As a novel noninvasive therapeutic modality combining low‐intensity ultrasound and
sonosensitizers, sonodynamic therapy (SDT) is promising for clinical translation due to its …

Intratumoral immunosuppressive microenvironment (ISM) remains the dominant limitation to
disable oncological immunotherapy such as immunogenic cell death (ICD). To resolve the …

Immunotherapy that harnesses the power of the immune system to eliminate malignant cells
has offered an effective approach for cancer treatment. However, limited patient response …