Glaucoma: management and future perspectives for nanotechnology-based treatment modalities

NM El Hoffy, EAA Azim, RM Hathout, MA Fouly… - European journal of …, 2021 - Elsevier
Glaucoma, being asymptomatic for relatively late stage, is recognized as a worldwide cause
of irreversible vision loss. The eye is an impervious organ that exhibits natural anatomical …

Recent advances in the excipients used for modified ocular drug delivery

M Koutsoviti, A Siamidi, P Pavlou, M Vlachou - Materials, 2021 - mdpi.com
In ocular drug delivery, maintaining an efficient concentration of the drug in the target area
for a sufficient period of time is a challenging task. There is a pressing need for the …

Tailoring terpesomes and leciplex for the effective ocular conveyance of moxifloxacin hydrochloride (Comparative assessment): in-vitro, ex-vivo, and in-vivo evaluation

R Albash, MM Abdellatif, M Hassan… - International Journal of …, 2021 - Taylor & Francis
Aim To compare the ability of both terpesomes (TPs) and leciplex (LPs) loaded moxifloxacin
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …

Formulation and characterization of acetazolamide/carvedilol niosomal gel for glaucoma treatment: in vitro, and in vivo study

R Abdelmonem, SF Elhabal, NS Abdelmalak… - Pharmaceutics, 2021 - mdpi.com
Acetazolamide (ACZ) is a diuretic used in glaucoma treatment; it has many side effects.
Carvedilol (CAR) is a non-cardioselective beta-blocker used in the treatment of elevated …

[HTML][HTML] Bioavailability enhancement of nanostructured microparticles of carvedilol

C Prieto, Z Evtoski, M Pardo-Figuerez… - Journal of Drug Delivery …, 2021 - Elsevier
A high throughput encapsulation technique termed as electrospraying assisted by
pressurized gas technology (EAPG) was used to produce nano-within-micro structures of a …