Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

Virus-induced senescence is a driver and therapeutic target in COVID-19

S Lee, Y Yu, J Trimpert, F Benthani, M Mairhofer… - Nature, 2021 - nature.com
Derailed cytokine and immune cell networks account for the organ damage and the clinical
severity of COVID-19 (refs.,,–). Here we show that SARS-CoV-2, like other viruses, evokes …

Potential clinical benefits of quercetin in the early stage of COVID-19: results of a second, pilot, randomized, controlled and open-label clinical trial

F Di Pierro, S Iqtadar, A Khan… - … journal of general …, 2021 - Taylor & Francis
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
cause of the ongoing global pandemic known as COVID-19. Based on the potential antiviral …

TRP channels in COVID-19 disease: potential targets for prevention and treatment

SM Jaffal, MA Abbas - Chemico-Biological Interactions, 2021 - Elsevier
Abstract Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe
acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry …

Transient receptor potential vanilloid subtype 1: potential role in infection, susceptibility, symptoms and treatment of COVID-19

F Liviero, M Campisi, P Mason, S Pavanello - Frontiers in Medicine, 2021 - frontiersin.org
The battle against the new coronavirus that continues to kill millions of people will be still
long. Novel strategies are demanded to control infection, mitigate symptoms and treatment …

Characterization of the Trans-Epithelial Transport of Green Tea (C. sinensis) Catechin Extracts with In Vitro Inhibitory Effect against the SARS-CoV-2 Papain-like …

CM Montone, SE Aita, A Arnoldi, AL Capriotti… - Molecules, 2021 - mdpi.com
This work describes an untargeted analytical approach for the screening, identification, and
characterization of the trans-epithelial transport of green tea (Camellia sinensis) catechin …

Characteristics of published/registered clinical trials on COVID-19 treatment: A systematic review

P Asili, M Mirahmad, O Tabatabaei-Malazy… - DARU Journal of …, 2021 - Springer
Objectives Due to the rapid spread of COVID-19 worldwide, many countries have designed
clinical trials to find efficient treatments. We aimed to critically report the characteristics of all …

Molecular mechanisms of possible action of phenolic compounds in COVID-19 protection and prevention

N Gligorijevic, M Radomirovic, O Nedic… - International Journal of …, 2021 - mdpi.com
The worldwide outbreak of COVID-19 was caused by a pathogenic virus called Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Therapies against SARS-CoV-2 …

[HTML][HTML] Modifiable risk factors for SARS-CoV-2

M Simon, J Pizzorno, J Katzinger - Integrative Medicine: A …, 2021 - ncbi.nlm.nih.gov
As the COVID-19 pandemic has raged on, considerable research has been performed
around the world evaluating the environmental, genetic, lifestyle, and nutritional factors that …

[HTML][HTML] Retrospective study of outcomes and hospitalization rates of patients in Italy with a confirmed diagnosis of early COVID-19 and treated at home within 3 days …

S Fazio, P Bellavite, E Zanolin… - … medical journal of …, 2021 - ncbi.nlm.nih.gov
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a
Confirmed Diagnosis of Early COVID-19 and Treated at Home Within 3 Days or After 3 Days of …