Polygenic risk scores (PRS) can provide useful information for personalized risk stratification
and disease risk assessment, especially when combined with non-genetic risk factors …

Obesity is the result of interactions between genes and environmental factors. Since
monogenic etiology is only known in some obesity-related genes, a genetic risk score (GRS) …

We test whether genetic influences that explain individual differences in aggression in early
life also explain individual differences across the life-course. In two cohorts from The …

Background Associations have been observed among genetic variants, dietary patterns, and
metabolic syndrome (MetS). A gap in knowledge is whether a genetic risk score (GRS) and …

Polygenic risk models have led to significant advances in understanding complex diseases
and their clinical presentation. While polygenic risk scores (PRS) can effectively predict …

Background There is growing support for the use of genetic risk scores (GRS) in routine
clinical settings. Due to the limited diversity of current genomic discovery samples, there are …

Identifying the mechanisms linking early experiences, genetic risk factors, and their
interaction with later health consequences is central to the development of preventive …

Obesity is an outcome of multiple factors including environmental and genetic influences.
Common obesity is a polygenic trait indicating that multiple genetic variants act …

Background Despite advances in cardiovascular disease and risk factor management,
mortality from ischemic heart failure (HF) in patients with coronary artery disease (CAD) …

Purpose The development of metabolic diseases such as type 2 diabetes (T2D) is closely
linked to a complex interplay between genetic and dietary factors. The prevalence of …