Stroke is a leading cause of disability, dementia and death worldwide. Approximately 70% of
deaths from stroke and 87% of stroke-related disability occur in low-income and middle …

New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use. Despite …

Admixed populations are routinely excluded from genomic studies due to concerns over
population structure. Here, we present a statistical framework and software package, Tractor …

The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

The differential spread and impact of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), causing Coronavirus Disease 2019 (COVID-19), across regions is a major …

The expansion of anatomically modern humans (AMHs) from Africa around 65,000 to 45,000
y ago (ca. 65 to 45 ka) led to the establishment of present-day non-African populations …

Minority and underresourced communities experience disproportionately high rates of fatal
cancer and cardiovascular disease. The intersection of these disparities within the …

F ST and kinship are key parameters often estimated in modern population genetics studies
in order to quantitatively characterize structure and relatedness. Kinship matrices have also …

Breast cancer is the commonest cause of global cancer-related deaths in women and a
public health burden in sub-Saharan Africa (SSA). Although the disease incidence in SSA …