Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …

Ageing of the immune system, or immunosenescence, contributes to the morbidity and
mortality of the elderly,. To define the contribution of immune system ageing to organism …

The environmental problem of Microplastics (MPs) pollution poses a great threat to human
and animal health, which has attracted global attention. The physiological integrity of …

The retina experiences increased oxidative stress in diabetes, and the transcriptional activity
of Nrf2, which is critical in regulating many antioxidant genes, is decreased. The nuclear …

The ovarian system comprises vital organs in females and is of great significance for the
maintenance of reproductive potential and endocrine stability. Although complex …

Aging is inevitable, but the inherently and genetically programmed aging process is
markedly influenced by environmental factors. All organisms are constantly exposed to …

Purinergic signaling is a cell communication pathway mediated by extracellular nucleotides
and nucleosides. Tri-and diphosphonucleotides are released in physiological and …

Large differences in COVID‐19 death rates exist between countries and between regions of
the same country. Some very low death rate countries such as Eastern Asia, Central Europe …

Senescence limits the characteristics and functionality of mesenchymal stem cells (MSCs),
thereby severely restricting their application in tissue engineering. Here, we investigated …