Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …

The CCR7 chemokine axis is comprised of chemokine ligand 21 (CCL21) and chemokine
ligand 19 (CCL19) acting on chemokine receptor 7 (CCR7). This axis plays two important …

Lipids, which along with carbohydrates and proteins are among the most important nutrients
for the living organism, have a variety of biological functions that can be applied widely in …

GM3, a typical tumor-associated carbohydrate antigen, is considered as an important target
for cancer vaccine development, but its low immunogenicity limits its application. αGalCer …

Conventional αβ CAR-T cell-based approaches have revolutionized the field of cancer
immunotherapy, but hurdles remain, especially for solid tumors. Novel strategies in …

The deleterious effects of psychological stress on mainstream T lymphocytes are well
documented. However, how stress impacts innate-like T cells is unclear. We report that long …

Cell-based cancer immunotherapy has revolutionized the treatment of hematological
malignancies. Specifically, autologous chimeric antigen receptor-engineered T (CAR-T) cell …

Pregnancy reprograms mammary epithelial cells (MECs) to control their responses to
pregnancy hormone re-exposure and carcinoma progression. However, the influence of …

Immunotherapy is now considered an innovative and strong strategy to beat metastatic, drug-
resistant, or relapsing tumours. It is based on the manipulation of several mechanisms …

Recently, cell‐mediated immune response in malignant neoplasms has become the focus in
immunotherapy against cancer. However, in leukemia, most studies on the cytotoxic …