The number of elderly multiple sclerosis (MS) patients is growing, mainly due to the increase
in the life expectancy of the general population and the availability of effective disease …

The high prevalence of post-acute sequelae of SARS-CoV-2 infection (PASC) is a significant
health concern. In particular, virus-specific immunity in patients who suffer from chronic …

Background Immune involvement is well-described in Parkinson's disease (PD), including
an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson's disease …

Ageing dramatically affects number and function of both innate and adaptive arms of
immune system, particularly T cell subsets, contributing to reduced vaccination efficacy …

Background Whether latent cytomegalovirus (CMV) infection in older adults has any
substantial health consequences is unclear. Here, we sought associations between CMV …

Cytomegalovirus (CMV) infection has a major impact on the T-cell pool, which is thought to
be associated with ageing of the immune system. The effect on the T-cell pool has been …

The induction of a specific antibody response has long been accepted as a serological
hallmark of recent infection or antigen exposure. Much of our understanding of the influenza …

Latent infection with cytomegalovirus (CMV) is assumed to contribute to the age-associated
decline of the immune system. CMV induces large changes in the T-cell pool and may …

HCMV drives complex and multiple cellular immune responses, which causes a persistent
immune imprint in hosts. This study aimed to achieve both a quantitative determination of the …

Immunosenescence is the general term used to describe the aging-associated decline of
immunological function that explains the higher susceptibility to infectious diseases and …